期刊
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
卷 75, 期 6, 页码 1793-1804出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.bjps.2022.02.053
关键词
Breast reconstruction; Mastectomy; Diabetes; Surgical outcomes
类别
Diabetes mellitus poses a higher risk of complications in patients undergoing breast reconstruction after mastectomy, including surgical complications, infection, and tissue necrosis.
in English. Outcomes evaluated were overall complications, surgical complications, and longer hospital stay. Subgroup analysis investigated outcomes, such as implant/flap failure, infection, and necrosis. Results: Sixty-five studies met our inclusion criteria and 38 provided data to be included in the meta-analysis. A total of 151,585 patients were included, of which 9299 had diabetes. Women with diabetes were more likely to experience overall complications (11.6% vs 5.6%; p symbolscript 0.0001) and surgical complications (7.7% vs 3.3%; p symbolscript 0.0001), and were more likely to have a prolonged hospital stay ( p symbolscript 0.04) than women without diabetes. Subgroup analysis showed that implant loss (2.5% vs 1.6%; p symbolscript 0.0003), infection (6.8% vs 2.5%; p symbolscript 0.0001) and necrosis (23.8% vs 6.5; p symbolscript 0.001) were significantly higher in women with diabetes. Conclusions: This study provides evidence that diabetes mellitus increases the risk of compli-cations in patients with breast cancer undergoing BR after mastectomy. Prospective studies are required to establish whether diabetes that is well-controlled prior to reconstruction, including diabetes that is paired with adjuvant radiation therapy, reduces the perioperative risks. (c) 2022 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by El-sevier Ltd. All rights reserved.
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