4.6 Editorial Material

The heat is on! TRPV1 channels and resistance artery myogenic tone

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Review Physiology

Myogenic Tone in Peripheral Resistance Arteries and Arterioles: The Pressure Is On!

William F. Jackson

Summary: Resistance arteries and arterioles in the peripheral microcirculation play crucial roles in controlling blood pressure, blood flow distribution, and vascular resistance, with myogenic tone being a hallmark feature. However, our understanding of the signaling pathways underlying this key microvascular property remains incomplete, with emphasis on the roles of G-protein-coupled receptors, ion channels, and various kinases in the activity of vascular smooth muscle cells.

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