4.5 Article

Interferon activated gene 204 (Ifi204) protects against bone loss in experimental periodontitis

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Rheumatology

Efficacy and Safety of E6011, an Anti-Fractalkine Monoclonal Antibody, in Patients With Active Rheumatoid Arthritis With Inadequate Response to Methotrexate: Results of a Randomized, Double-Blind, Placebo-Controlled Phase II Study

Yoshiya Tanaka et al.

Summary: The study evaluated the efficacy and safety of E6011, a humanized IgG2 monoclonal antibody against human fractalkine, in RA patients in a phase II trial. E6011 demonstrated modest effectiveness in RA patients over 24 weeks of treatment, with statistically significant improvements seen in the ACR20 response rates in the 200-mg and 400/200-mg groups at week 24. Subgroup analysis showed greater efficacy of E6011 in patients with a higher baseline proportion of CD16+ monocytes.

ARTHRITIS & RHEUMATOLOGY (2021)

Article Dentistry, Oral Surgery & Medicine

Impaired function of epithelial plakophilin-2 is associated with periodontal disease

Ning Yu et al.

Summary: The study found that the expression of PKP2 in gingival biopsies of periodontitis patients was significantly lower compared to healthy controls. PKP2 is crucial for maintaining gingival epithelial barrier function, and P.gingivalis impairs epithelial barrier function by promoting PKP2 degradation.

JOURNAL OF PERIODONTAL RESEARCH (2021)

Review Dentistry, Oral Surgery & Medicine

Genomics of periodontal disease and tooth morbidity

Thiago Morelli et al.

PERIODONTOLOGY 2000 (2020)

Review Dentistry, Oral Surgery & Medicine

Role of inflammasomesin the pathogenesis of periodontal disease and therapeutics

Julie T. Marchesan et al.

PERIODONTOLOGY 2000 (2020)

Article Dentistry, Oral Surgery & Medicine

Flossing Is Associated with Improved Oral Health in Older Adults

J. T. Marchesan et al.

JOURNAL OF DENTAL RESEARCH (2020)

Article Biochemistry & Molecular Biology

The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research

Nathalie Percie du Sert et al.

PLOS BIOLOGY (2020)

Article Dentistry, Oral Surgery & Medicine

IL-37-and IL-35/IL-37-Producing Plasma Cells in Chronic Periodontitis

L. Jing et al.

JOURNAL OF DENTAL RESEARCH (2019)

Article Multidisciplinary Sciences

RNA-Seq analysis of interferon inducible p204-mediated network in anti-tumor immunity

Jinlong Jian et al.

SCIENTIFIC REPORTS (2018)

Article Biochemistry & Molecular Biology

Inhibition of AIM2 inflammasome activation by a novel transcript isoform of IFI16

Pei-Hui Wang et al.

EMBO REPORTS (2018)

Article Biochemical Research Methods

An experimental murine model to study periodontitis

Julie Marchesan et al.

NATURE PROTOCOLS (2018)

Article Multidisciplinary Sciences

GWAS for Interleukin-1 beta levels in gingival crevicular fluid identifies IL37 variants in periodontal inflammation

Steven Offenbacher et al.

NATURE COMMUNICATIONS (2018)

Article Immunology

A noncanonical function of cGAMP in inflammasome priming and activation

Karen V. Swanson et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2017)

Article Dentistry, Oral Surgery & Medicine

Common Polymorphisms in IFI16 and AIM2 Genes Are Associated With Periodontal Disease

Julie T. Marchesan et al.

JOURNAL OF PERIODONTOLOGY (2017)

Review Dentistry, Oral Surgery & Medicine

Quo vadis: what is the future of periodontics? How will we get there?

Kenneth S. Kornman et al.

PERIODONTOLOGY 2000 (2017)

Article Gastroenterology & Hepatology

Strong Upregulation of AIM2 and IFI16 Inflammasomes in the Mucosa of Patients with Active Inflammatory Bowel Disease

Wiebe Vanhove et al.

INFLAMMATORY BOWEL DISEASES (2015)

Article Immunology

cGAS and Ifi204 Cooperate To Produce Type I IFNs in Response to Francisella Infection

Kelly M. Storek et al.

JOURNAL OF IMMUNOLOGY (2015)

Review Biochemistry & Molecular Biology

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA

Benjamin A. Diner et al.

MOLECULAR SYSTEMS BIOLOGY (2015)

Article Biochemistry & Molecular Biology

Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt

Justin E. Wilson et al.

NATURE MEDICINE (2015)

Editorial Material Medicine, General & Internal

Precision Medicine - Personalized, Problematic, and Promising

J. Larry Jameson et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Article Microbiology

Induction of Bone Loss by Pathobiont-Mediated Nod1 Signaling in the Oral Cavity

Yizu Jiao et al.

CELL HOST & MICROBE (2013)

Article Biochemistry & Molecular Biology

Exploring the genetic basis of chronic periodontitis: a genome-wide association study

Kimon Divaris et al.

HUMAN MOLECULAR GENETICS (2013)

Article Immunology

Resolvin E1 and Chemokine-like Receptor 1 Mediate Bone Preservation

Li Gao et al.

JOURNAL OF IMMUNOLOGY (2013)

Article Multidisciplinary Sciences

Prevention of inflammation-mediated bone loss in murine and canine periodontal disease via recruitment of regulatory lymphocytes

Andrew J. Glowacki et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Rheumatology

Porphyromonas gingivalis oral infection exacerbates the development and severity of collagen-induced arthritis

Julie Teresa Marchesan et al.

ARTHRITIS RESEARCH & THERAPY (2013)

Article Dentistry, Oral Surgery & Medicine

Genome-wide Association Study of Periodontal Pathogen Colonization

K. Divaris et al.

JOURNAL OF DENTAL RESEARCH (2012)

Article Immunology

IFI16 is an innate immune sensor for intracellular DNA

Leonie Unterholzner et al.

NATURE IMMUNOLOGY (2010)

Article Oncology

C-C chemokine receptor 5 on stromal cells promotes pulmonary metastasis

HW van Deventer et al.

CANCER RESEARCH (2005)