Easy C sp 2-C sp2 reductive elimination from organoplatinum complexes by electrophilic fluorinating reagents

Electrophilic fluorination of bisaryl-platinum(II) complexes at RT leads to an exceptionally fast Ar-Ar instead of Ar-F reductive elimination. By reacting bisphosphine bisaryl-platinum(II) complex with NFSI, the biaryl product was formed with > 90% yield within < 30 minutes at RT. Moreover, by experimental and computational studies, the influence of ancillary ligands on the Ar-Ar reductive elimination reaction was investigated by changing their steric and electronic effects. The stability of some platinum fluoride complexes in the presence of water was also investigated. (c) 2022 Elsevier B.V. All rights reserved.

Automated summary

In this study, the electrophilic fluorination of bisaryl-platinum(II) complexes leading to an unusually fast Ar-Ar reductive elimination reaction instead of Ar-F elimination was investigated. The bisphosphine bisaryl-platinum(II) complex reacted with NFSI to produce the biaryl product with a yield of over 90% within less than 30 minutes at room temperature. Additionally, the influence of ancillary ligands on the Ar-Ar reductive elimination reaction was studied by modifying their steric and electronic effects, and the stability of some platinum fluoride complexes in the presence of water was also examined.