Visible-Light Enabled C(sp3)-C(sp2) Cross-Electrophile Coupling via Synergistic Halogen-Atom Transfer (XAT) and Nickel Catalysis

We herein report the first visible-light-mediated cross-coupling of unactivated alkyl iodides with aryl bromides through synergistic halogen atom transfer (XAT) and nickel catalysis. This simple protocol operates under mild reaction conditions and tolerates avariety of functional groups affording C(sp3)-C(sp2) cross-coupling products in good to moderate yields

Automated summary

This study presents a novel method for the visible-light-mediated cross-coupling of unactivated alkyl iodides with aryl bromides, through synergistic halogen atom transfer (XAT) and nickel catalysis.