Carboxylic Acid Functionalization Using Sulfoxonium Ylides as a Carbene Source

Functionalization of carboxylic acids using sulfoxo-nium ylides in the presence of [VO(acac)(2)] as a catalyst is reported. The usual carbene source, diazo compounds, failed to produce alpha-carbonyloxy esters in good yield when compared to sulfoxonium ylides. Various standard spectroscopic and analytical techniques were used to characterize the products formed.

Automated summary

Functionalization of carboxylic acids using sulfoxonium ylides in the presence of [VO(acac)(2)] as a catalyst is reported. Compared to the usual carbene source, diazo compounds, sulfoxonium ylides were found to produce alpha-carbonyloxy esters in better yield. Various standard spectroscopic and analytical techniques were utilized to characterize the formed products.