A Removable Acyl Group Promoted the Intramolecular Dehydro-Diels-Alder Reaction of Styrene-Ynes: Highly Chemoselective Synthesis of Aryldihydronaphthalene Derivatives

A removable acyl group promoted the intramolecular didehydro-Diels-Alder reaction of styrene-ynes under mild reaction conditions is proposed. The reaction is free of metals and catalysts, is easy to perform, and exhibits good functional group tolerance, providing a highly chemoselective approach for obtaining the valuable aryldihydronaphthalene derivatives.

Automated summary

A method for obtaining valuable aryldihydronaphthalene derivatives is proposed, using a removable acyl group to promote the intramolecular didehydro-Diels-Alder reaction of styrene-ynes under mild reaction conditions. The reaction is metal-free, catalyst-free and has good functional group tolerance.