Congress of neurological surgeons systematic review and evidence-based guidelines update on the role of cytoreductive surgery in the management of progressive glioblastoma in adults

Question In patients with previously diagnosed glioblastoma who are suspected of experiencing progression, does repeat cytoreductive surgery improve progression free survival or overall survival compared to alternative interventions? Target population These recommendations apply to adults with previously diagnosed glioblastoma who are suspected of experiencing progression of the neoplastic process and are amenable to surgical resection. Recommendation Level II: Repeat cytoreductive surgery is recommended in progressive glioblastoma patients to improve overall survival.

Automated summary

Repeat cytoreductive surgery is recommended for patients with progressive glioblastoma to improve overall survival, especially in cases where progression is suspected.