4.6 Article Retracted Publication

被撤回的出版物: Two photoluminescent Zn(II) complexes: Protection evaluation against cancer disease by reducing activation of PI3K/Akt signaling pathway (Retracted article. See vol. 1277, 2023)

期刊

JOURNAL OF MOLECULAR STRUCTURE
卷 1256, 期 -, 页码 -

出版社

ELSEVIER
DOI: 10.1016/j.molstruc.2022.132484

关键词

Zn(II) compound; Solvothermal synthesis; Luminescence; Cancer

资金

  1. project of Science and Technology Commission Shanghai Municipality [18401900100]

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Two novel compounds based on Zn(II) were synthesized using a mixed-ligand strategy, and their solid luminescent properties were achieved by tuning the auxiliary N-donor ligand.
Through utilizing a mixed-ligand strategy, two novel compounds based on Zn(II), that is [Zn(L)(bpe)](n).5n(H2O) ( 1 ) and [Zn(L)(bpp)]n ( 2 ) (H2L is = 5-(1-oxoisoindolin-2-yl)isophthalic acid, bpe is 1,2-bis(4-pyridyl)ethane, and bpp is 1,3-bis(4-pyridyl)propane), are solvothermally generated via tuning the auxiliary N-donor ligand. The above compounds' solid luminescent emission spectra show intense L2- ligand-centered emission bands at room temperature. For treating the cancer disease, real time RT-PCR was exploited for detecting PI3K/Akt signaling pathway activation in myocardium. In addition to this, the flow cytometry was employed for measuring the percentage of the apoptotic cancer cells. (C)& nbsp;2022 Elsevier B.V. All rights reserved.

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