Synthesis and structure elucidation of thiopyrano[2,3-d ]thiazole-6-carbonitriles as adducts of Michael reaction

A series of thiopyrano[2,3d]thiazole derivatives via Michael reaction of malononitrile and 5arylideneisorhodanine were synthesized. The further acid or alkaline hydrolysis of obtained thiopyrano[2,3d]thiazole-6-carbonitrile led to starting 5-arylideneisorhodanine. The structures of newly synthesized compounds were established by spectral data and a single-crystal X-ray diffraction analysis. (c) 2022 Elsevier B.V. All rights reserved.

Automated summary

A series of thiopyrano[2,3d]thiazole derivatives were synthesized via Michael reaction of malononitrile and 5arylideneisorhodanine. The structures of the newly synthesized compounds were established using spectral data and single-crystal X-ray diffraction analysis.