An isothermal amplification-coupled dipstick for the rapid detection of COVID-19

Review Biochemical Research Methods

Review of analytical performance of COVID-19 detection methods

Basant Giri et al.

Summary: In the recent COVID-19 pandemic, various diagnostic methods have been developed for detecting the virus, with factors such as throughput, infrastructure requirements, and analytical performance varying between methods. Selecting a reliable and rapid diagnostic method is crucial for making appropriate decisions and implementing effective public health interventions.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2021)

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Review Medicine, General & Internal

Comparison of Saliva and Nasopharyngeal Swab Nucleic Acid Amplification Testing for Detection of SARS-CoV-2 A Systematic Review and Meta-analysis

Guillaume Butler-Laporte et al.

Summary: This study evaluated the diagnostic accuracy of saliva NAAT for COVID-19 and found that its accuracy is similar to that of nasopharyngeal swab NAAT, especially in ambulatory settings. This suggests the potential for saliva NAAT as an alternative to nasopharyngeal swabs and supports further research in this area.

JAMA INTERNAL MEDICINE (2021)

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Review Chemistry, Physical

Diagnostics for SARS-CoV-2 infections

Bhavesh D. Kevadiya et al.

Summary: The outbreak of SARS-CoV-2 causing COVID-19 has led to diverse and severe symptoms, making accurate diagnosis a key challenge. Rapid diagnosis and treatment measures are crucial in controlling the spread of the virus. The development of diagnostic tools, including nanomaterial-based ones, is essential in the fight against the pandemic.

NATURE MATERIALS (2021)

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Article Multidisciplinary Sciences

Limit of detection in different matrices of 19 commercially available rapid antigen tests for the detection of SARS-CoV-2

Ana Cubas-Atienzar et al.

Summary: In this study, an independent evaluation was conducted on the limit of detection (LOD) of 19 marketed Ag-RDTs, revealing that most tests performed well with direct culture supernatant but showed decreased sensitivity in Amies media. Additionally, after 7 days of storage at -80 degrees C, some tests exhibited reduced efficiency on stored dilutions of SARS-CoV-2.

SCIENTIFIC REPORTS (2021)

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Article Microbiology