4.6 Review

Vanadium complexes with polypyridyl ligands: Speciation, structure and potential medicinal activity

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JOURNAL OF INORGANIC BIOCHEMISTRY
卷 229, 期 -, 页码 -

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ELSEVIER SCIENCE INC
DOI: 10.1016/j.jinorgbio.2022.111712

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Vanadium; Vanadium-based complexes; Polypyridyl ligands; Anticancer activity; Speciation studies; Cytotoxicity

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This review focuses on the interaction between the essential element vanadium and 1,10-phenanthroline and polypyridyl ligands. It summarizes prior work on speciation studies for the vanadium-phenanthroline binary systems and hydrolytic studies of the metal ion. It also provides a comprehensive overview of different X-ray structures known to date and discusses the potential cytotoxic activity of vanadium-polypyridyl complexes.
This review focuses on the interaction between the essential element-vanadium with 1,10-phenanthroline and polypyridyl ligands. It starts with a summary of the prior work on speciation studies for the binary systems vanadium-phenanthroline alongside several hydrolytic studies of the metal ion. It also includes a complete overview on the different X-ray structures known to date with discussions on the potential cytotoxic activity of several vanadium-polypyridyl complexes.

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