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JOURNAL OF ENDOCRINOLOGY (2019)
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NATURE GENETICS (2019)
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CELL METABOLISM (2018)
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CELL STEM CELL (2018)
FoxO1 inhibition promotes differentiation of human embryonic stem cells into insulin producing cells
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EXPERIMENTAL CELL RESEARCH (2018)
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JOURNAL OF CLINICAL INVESTIGATION (2017)
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JOURNAL OF CLINICAL INVESTIGATION (2017)
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SCIENTIFIC REPORTS (2017)
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CELL METABOLISM (2017)
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GENES & DEVELOPMENT (2016)
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NATURE COMMUNICATIONS (2016)
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EMBO JOURNAL (2014)
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GENES & DEVELOPMENT (2013)
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JOURNAL OF CLINICAL INVESTIGATION (2013)
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GENESIS (2012)
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JOURNAL OF ENDOCRINOLOGY (2012)
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NATURE GENETICS (2012)
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
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EMBO JOURNAL (2011)
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ENDOCRINOLOGY (2011)
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NATURE REVIEWS IMMUNOLOGY (2011)
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MOLECULAR PHARMACOLOGY (2010)
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NATURE GENETICS (2010)
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CELL (2009)
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DEVELOPMENTAL CELL (2009)
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JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
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NATURE GENETICS (2009)
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METABOLISM-CLINICAL AND EXPERIMENTAL (2009)
pdx-1 function is specifically required in embryonic cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis
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DEVELOPMENTAL BIOLOGY (2008)
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GENES & DEVELOPMENT (2008)
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Amanda M. Vanhoose et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Histone deacetylase inhibitors modify pancreatic cell fate determination and amplify endocrine progenitors
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MOLECULAR AND CELLULAR BIOLOGY (2008)
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Francis C. Lynn et al.
DIABETES (2007)
Foxa2 controls vesicle docking and insulin secretion in mature β cells
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CELL METABOLISM (2007)
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DEVELOPMENTAL CELL (2007)
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Patrick Collombat et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
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DEVELOPMENTAL BIOLOGY (2006)
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DEVELOPMENTAL BIOLOGY (2006)
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Catherine V. T. Chin-Chance et al.
JOURNAL OF INVESTIGATIVE MEDICINE (2006)
Targeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation
Y Fujitani et al.
GENES & DEVELOPMENT (2006)
Interactions between areas I and II direct pdx-1 expression specifically to islet cell types of the mature and developing pancreas
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JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
FoxO1 protects against pancreatic β cell failure through NeuroD and MafA induction
YI Kitamura et al.
CELL METABOLISM (2005)
Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of β-cell differentiation and secretory function in the db/db mouse model of diabetes
C Kjorholt et al.
DIABETES (2005)
IPF-1/MODY4 gene missense mutation in an Italian family with type 2 and gestational diabetes
C Gragnoli et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2005)
The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the α- and β-cell lineages in the mouse endocrine pancreas
P Collombat et al.
DEVELOPMENT (2005)
MafA is a key regulator of glucose-stimulated insulin secretion
C Zhang et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells
JC Schisler et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Oxidative stress-mediated, post-translational loss of MafA protein as a contributing mechanism to loss of insulin gene expression in glucotoxic beta cells
JS Harmon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Identification of a novel PDX-1 binding site in the human insulin gene enhancer
J Le Lay et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Conditional inactivation of Pax6 in the pancreas causes early onset of diabetes
R Ashery-Padan et al.
DEVELOPMENTAL BIOLOGY (2004)
beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes
AE Butler et al.
DIABETES (2003)
MafA is a glucose-regulated and pancreatic β-cell-specific transcriptional activator for the insulin gene
K Kataoka et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
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DIABETOLOGIA (2002)
The role of hepatic nuclear factor 1α and PDX-1 in transcriptional regulation of the pdx-1 gene.
K Gerrish et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
A missense mutation of Pax4 gene (R121W) is associated with type 2 diabetes in Japanese
Y Shimajiri et al.
DIABETES (2001)
Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia
S Ferber et al.
NATURE MEDICINE (2000)
neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas
G Gradwohl et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Pancreatic β cell-specific transcription of the pdx-1 gene -: The role of conserved upstream control regions and their hepatic nuclear factor 3β sites
K Gerrish et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
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DIABETES (2000)
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