Increasing Racial and Ethnic Diversity in Cancer Clinical Trials: An American Society of Clinical Oncology and Association of Community Cancer Centers Joint Research Statement

Editorial Material Medicine, General & Internal

Combating Structural Inequities - Diversity, Equity, and Inclusion in Clinical and Translational Research

L. Ebony Boulware et al.

NEW ENGLAND JOURNAL OF MEDICINE (2022)

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Editorial Material Medicine, General & Internal

Research Participation in Marginalized Communities - Overcoming Barriers

Katrina Armstrong et al.

NEW ENGLAND JOURNAL OF MEDICINE (2022)

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Article Oncology

When Offered to Participate: A Systematic Review and Meta-Analysis of Patient Agreement to Participate in Cancer Clinical Trials

Joseph M. Unger et al.

Summary: The study found that more than half of cancer patients offered clinical trials actually choose to participate. Factors such as race and type of treatment did not significantly affect participation rates. The main reasons for nonparticipation were treatment choice or lack of interest.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2021)

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Editorial Material Oncology

Revisiting Barriers to Clinical Trials Accrual

Michael D. Brundage

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2021)

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Article

The Ethical Imperative of Equity in Oncology: Lessons Learned From 2020 and a Path Forward

Jonathan M. Marron et al.

American Society of Clinical Oncology educational book / ASCO. American Society of Clinical Oncology. Meeting (2021)

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Article Oncology

American Society of Clinical Oncology Road to Recovery Report: Learning From the COVID-19 Experience to Improve Clinical Research and Cancer Care

Nathan A. Pennell et al.

Summary: ASCO's evaluation and recommendations for clinical research and cancer care delivery during the pandemic aim to improve fairness, accessibility, and efficiency, protect patient safety, and maintain data quality.

JOURNAL OF CLINICAL ONCOLOGY (2021)

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Article Oncology

Continuing to Broaden Eligibility Criteria to Make Clinical Trials More Representative and Inclusive: ASCO-Friends of Cancer Research Joint Research Statement

Edward S. Kim et al.

Summary: The purpose of broadening clinical trial eligibility criteria is to increase the inclusivity and representativeness of trial populations, with the goal of making evidence more informative for a broader patient population. Implementation of these recommendations is intended to ease patient eligibility determination and accelerate clinical trial accrual.

CLINICAL CANCER RESEARCH (2021)

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Editorial Material Medicine, General & Internal

Integrating Research into Community Practice - Toward Increased Diversity in Clinical Trials

Janet Woodcock et al.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

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Article Multidisciplinary Sciences

Development of a web tool to increase research literacy in underserved populations through public library partnerships

Melissa A. Simon et al.

Summary: The development of the website "Health for All" aims to enhance racial/ethnic minority participation in clinical trials by providing research literacy and addressing distrust caused by longstanding racism and discrimination through a hybridized single-scrolling and guided module prototype.

PLOS ONE (2021)

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Article Medicine, General & Internal

Racial and Ethnic Disparities Among Participants in Precision Oncology Clinical Studies

Christopher M. Aldrighetti et al.

Summary: This study revealed a significant underrepresentation of racial and ethnic minority populations in precision oncology studies for breast, lung, prostate, and colorectal cancers, compared to their cancer incidence rates in the US population. Increasing diversity among study participants is crucial to ensure that all individuals can benefit from advancements in cancer research and personalized treatments.

JAMA NETWORK OPEN (2021)

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Article Oncology

Association of a Lay Health Worker-Led Intervention on Goals of Care, Quality of Life, and Clinical Trial Participation Among Low-Income and Minority Adults With Cancer

Manali Patel et al.

Summary: A lay health worker-led intervention showed improvements in supportive care, clinical trial participation, and health-related quality of life among low-income and minority adults with cancer. This intervention may help address disparities in cancer care outcomes.

JCO ONCOLOGY PRACTICE (2021)

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Article Oncology

African American participation in cancer clinical trials

Jordan Swaby et al.

Summary: Reasons for the lower participation rate of African Americans in cancer clinical trials often involve provider related issues, family concerns, health literacy and trust. Successful interventions to improve African American participation or address barriers typically revolve around community based participatory research and educational cancer clinical trial videos/tools.

ECANCERMEDICALSCIENCE (2021)

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Editorial Material Oncology

Promoting Inclusion of Members of Racial and Ethnic Minority Groups in Cancer Drug Development

Lola Fashoyin-Aje et al.

JAMA ONCOLOGY (2021)

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Article Oncology

Cancer Disparities and Black American Representation in Clinical Trials Leading to the Approval of Oral Chemotherapy Drugs in the United States Between 2009 and 2019

Veronica B. Ajewole et al.

Summary: The study evaluated the reporting of race and inclusion of Black Americans (BAs) in clinical trials leading to FDA approval of oral chemotherapy drugs from 2009 to 2019. It found that BAs were under-represented in these clinical trials, particularly in the trials of three cancer types with the highest disparity rates among this population.

JCO ONCOLOGY PRACTICE (2021)

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Article Oncology

Cancer Disparities and Black American Representation in Clinical Trials Leading to the Approval of Oral Chemotherapy Drugs in the United States Between 2009 and 2019

Veronica B. Ajewole et al.

Summary: This study evaluated the representation of Black Americans in clinical trials leading to FDA approval of oral chemotherapy drugs from 2009 to 2019, finding that Black Americans were under-represented in these trials.

JCO ONCOLOGY PRACTICE (2021)

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Review Oncology

Overcoming Barriers: Evidence-Based Strategies to Increase Enrollment of Underrepresented Populations in Cancer Therapeutic Clinical Trials-a Narrative Review

Iris Vuong et al.

JOURNAL OF CANCER EDUCATION (2020)

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Letter Oncology

Racial Disparities in Patient-Reported Measures of Physician Cultural Competency Among Cancer Survivors in the United States

Santino S. Butler et al.

JAMA ONCOLOGY (2020)

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Article Oncology

Bias and stereotyping among research and clinical professionals: Perspectives on minority recruitment for oncology clinical trials

Soumya J. Niranjan et al.

CANCER (2020)

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Article Medicine, Research & Experimental

Operational strategies in US cancer centers of excellence that support the successful accrual of racial and ethnic minorities in clinical trials

Jeanne M. Regnante et al.

CONTEMPORARY CLINICAL TRIALS COMMUNICATIONS (2020)

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Review Oncology

Systematic Review and Meta-Analysis of the Magnitude of Structural, Clinical, and Physician and Patient Barriers to Cancer Clinical Trial Participation

Joseph M. Unger et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2019)

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Article Oncology

US Cancer Centers of Excellence Strategies for Increased Inclusion of Racial and Ethnic Minorities in Clinical Trials

Jeanne M. Regnante et al.

JOURNAL OF ONCOLOGY PRACTICE (2019)

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Article Oncology

Addressing the Financial Burden of Cancer Clinical Trial Participation: Longitudinal Effects of an Equity Intervention

Ryan D. Nipp et al.

ONCOLOGIST (2019)

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Article Public, Environmental & Occupational Health

The Impact of an Educational Video on Clinical Trial Enrollment and Knowledge in Ethnic Minorities: A Randomized Control Trial

Jeannine S. Skinner et al.

FRONTIERS IN PUBLIC HEALTH (2019)

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Article Oncology

Disparity of Race Reporting and Representation in Clinical Trials Leading to Cancer Drug Approvals From 2008 to 2018

Jonathan M. Loree et al.

JAMA ONCOLOGY (2019)

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Letter Oncology

Laboratory Eligibility Criteria as Potential Barriers to Participation by Black Men in Prostate Cancer Clinical Trials

Marie E. Vastola et al.

JAMA ONCOLOGY (2018)

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Review Oncology

Representation of Minorities and Women in Oncology Clinical Trials: Review of the Past 14 Years

Narjust Duma et al.

JOURNAL OF ONCOLOGY PRACTICE (2018)

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Article Oncology

Addressing Financial Barriers to Patient Participation in Clinical Trials: ASCO Policy Statement

Karen M. Winkfield et al.

JOURNAL OF CLINICAL ONCOLOGY (2018)

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Article Oncology

Broadening Eligibility Criteria to Make Clinical Trials More Representative: American Society of Clinical Oncology and Friends of Cancer Research Joint Research Statement

Edward S. Kim et al.

JOURNAL OF CLINICAL ONCOLOGY (2017)

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Editorial Material Medicine, General & Internal

Reevaluating Eligibility Criteria - Balancing Patient Protection and Participation in Oncology Trials

Julia A. Beaver et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

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Article Oncology

Video intervention increases participation of black breast cancer patients in therapeutic trials

Brandi N. Robinson et al.

NPJ BREAST CANCER (2017)

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Article Public, Environmental & Occupational Health

Enrolling Minority and Underserved Populations in Cancer Clinical Research

Sherrie F. Wallington et al.

AMERICAN JOURNAL OF PREVENTIVE MEDICINE (2016)

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Article Oncology

Patient Navigation As a Model to Increase Participation of African Americans in Cancer Clinical Trials

Mona N. Fouad et al.

JOURNAL OF ONCOLOGY PRACTICE (2016)

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Article Medicine, Research & Experimental

Patient participation in cancer clinical trials: A pilot test of lay navigation

Kathleen B. Cartmell et al.

CONTEMPORARY CLINICAL TRIALS COMMUNICATIONS (2016)

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Article Public, Environmental & Occupational Health

Adaptation of a Cancer Clinical Trials Education Program for African American and Latina/o Community Members

Debra J. Pelto et al.

HEALTH EDUCATION & BEHAVIOR (2016)

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Article Oncology

State- of- the- Science of Patient Navigation as a Strategy for Enhancing Minority Clinical Trial Accrual

Rahel G. Ghebre et al.

CANCER (2014)

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Article Oncology

Perspectives on Barriers and Facilitators to Minority Recruitment for Clinical Trials Among Cancer Center Leaders, Investigators, Research Staff, and Referring Clinicians: Enhancing Minority Participation in Clinical Trials ( EMPaCT)

Raegan W. Durant et al.

CANCER (2014)

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Article Oncology

An institutional strategy to increase minority recruitment to therapeutic trials

Victoria V. Anwuri et al.

CANCER CAUSES & CONTROL (2013)

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Article Oncology

The National Cancer Institute-American Society of Clinical Oncology Cancer Trial Accrual Symposium: Summary and Recommendations

Andrea M. Denicoff et al.

JOURNAL OF ONCOLOGY PRACTICE (2013)

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Article Medicine, Research & Experimental

A surveillance system for monitoring, public reporting, and improving minority access to cancer clinical trials

William R. Carpenter et al.

CLINICAL TRIALS (2012)

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Article Medicine, General & Internal

Participation in cancer clinical trials - Race-, sex-, and age-based disparities

VH Murthy et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2004)

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Increasing Racial and Ethnic Diversity in Cancer Clinical Trials: An American Society of Clinical Oncology and Association of Community Cancer Centers Joint Research Statement

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