Filling in the gaps: SNX-RGS proteins as multiorganelle tethers

SNX-RGS proteins are molecular tethers localized to multiple interorganelle contact sites that exhibit roles in cellular metabolism. Here, we highlight recent findings on these proteins and discuss their emerging roles in metabolism, human disease, and lipid trafficking.

Automated summary

This article discusses the important roles of SNX-RGS proteins in multiple interorganelle contact sites, as well as their emerging roles in cellular metabolism, human disease, and lipid trafficking.