期刊
INTERNATIONAL JOURNAL OF STROKE
卷 18, 期 2, 页码 193-200出版社
SAGE PUBLICATIONS LTD
DOI: 10.1177/17474930221094933
关键词
Diet; stroke; principal component analysis; West Africans
This study investigates the association between dietary patterns and stroke risk among West Africans and finds that plant-based diets are associated with a lower risk of stroke.
Background: The relationship of diet with stroke risk among Africans is not well understood. Aim: The aim of this study was to investigate the association between dietary patterns and stroke risk among West Africans. Methods: In this multi-center case-control study, 3684 stroke patients matched (for age and sex) with 3684 healthy controls were recruited from Nigeria and Ghana. Food consumption was assessed using a food frequency questionnaire, and dietary patterns were summarized using principal component analysis. Stroke was defined using predefined criteria primarily on clinical evaluation following standard guidelines. Conditional logistic regression was applied to compute odds ratio (OR) and 95% confidence interval (CI) for stroke risk by tertiles of dietary patterns adjusting for relevant confounders. Results: Overall, mean age was 59.0 +/- 13.9 years, and 3992 (54.2%) were males. Seven dietary patterns were identified. Multivariable-adjusted OR (95% CI) for risk of stroke by second and third tertiles (using the lowest and first tertile as reference) of dietary patterns was 1.65 (1.43, 1.90) and 1.74 (1.51, 2.02), for poultry product and organ meat; 1.69 (1.47, 1.96) and 1.51 (1.31, 1.75) for red meat; 1.07 (0.92, 1.23) and 1.21 (1.04, 1.40) for fried foods and sweetened drinks; 0.69 (0.60, 0.80) and 0.45 (0.39, 0.53) for vegetables; 0.84 (0.72, 0.97) and 0.81 (0.70, 0.93) for whole-grain and fruit drinks; and 0.97 (0.84, 1.12) and 0.85 (0.73, 0.98) for fruits respectively (p < 0.05). Conclusion: These data suggest that plant-based diets are associated with a lower risk of stroke and might be a beneficial dietary recommendation for the primary prevention of stroke among Africans.
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