4.3 Article

Design and fabrication of biodegradable electrospun nanofibers loaded with biocidal agents

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TAYLOR & FRANCIS AS
DOI: 10.1080/00914037.2021.2021905

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Electrospun nanofibers; biocidal agents; nanoparticles; biomedical applications; molecular dynamics; density functional theory

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Electrospinning is a versatile technique for fabricating nanofibers with various advantages. This article discusses the use of electrospun biodegradable polymer nanofibers in biomedical applications, including tissue engineering, wound dressing, and drug delivery. It also explores the interaction studies between polymers loaded with nanoparticles through computational studies.
Electrospinning, a versatile nanofiber processing technique, has acquired considerable attention over conventional nanofiber fabrication methods owing to its inherent advantages, such as reasonable control over fiber dimensions, scalability, process convenience, and applicability towards an extensive array of materials. Electrospun biodegradable polymer nanofibers based on Poly(vinyl alcohol) (PVA), Poly(beta-hydroxybutyrate-beta-hydroxyvalerate) (PHBV), Poly(lactic-co-glycolic acid) (PLGA), Polycaprolactone (PCL), and Polylactic acid (PLA) incorporating various biocidal agents for biomedical applications which embodies tissue engineering scaffolds, wound dressing and drug delivery would be addressed here. This review also provides an insight into computational studies of polymers loaded with nanoparticles to examine the interaction studies between them.

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