Early Alterations of Intra-Mural Elastic Lamellae Revealed by Synchrotron X-ray Micro-CT Exploration of Diabetic Aortas

Review Cardiac & Cardiovascular Systems

Vascular imaging of atherosclerosis: Strengths and weaknesses

Laura E. Mantella et al.

Summary: Atherosclerosis is an inflammatory disease that can lead to cardiovascular complications. Imaging techniques play a crucial role in identifying and quantifying atherosclerotic burden. Recent advances in microvascular imaging have proven to be important in atherosclerosis research.

ATHEROSCLEROSIS (2021)

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Review Physiology

Vascular Stiffness in Aging and Disease

Stephen F. Vatner et al.

Summary: The review focuses on understanding the increased vascular stiffness with aging and its contribution to major human diseases. It discusses differences in stiffness along the aortic tree and the divergent effects on males and females, particularly due to the protective role of female sex hormones. The review also highlights the importance of studying human and non-human primate data to explore mechanisms of age-related increases in vascular stiffness.

FRONTIERS IN PHYSIOLOGY (2021)

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Article Biochemistry & Molecular Biology

X-ray microtomography reveals a lattice-like network within aortic elastic lamellae

Aicha Ben Zemzem et al.

Summary: The arterial wall consists of three concentric layers with extracellular matrix providing support. Elastin, a major component of arterial ECM, forms a lattice-like network within the concentric elastic lamellae as revealed by 3D imaging.

FASEB JOURNAL (2021)

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Article Optics