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Increase in Both CD14-Positive and CD15-Positive Myeloid-Derived Suppressor Cell Subpopulations in the Blood of Patients With Glioma But Predominance of CD15-Positive Myeloid-Derived Suppressor Cells in Glioma Tissue
Paul R. Gielen et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2015)
Immunosuppressive mechanisms in glioblastoma
Edjah K. Nduom et al.
NEURO-ONCOLOGY (2015)
Preoperative neutrophil-lymphocyte count ratio helps predict the grade of glial tumor - A pilot study
Przemyslaw Zadora et al.
NEUROLOGIA I NEUROCHIRURGIA POLSKA (2015)
Glioma-Associated Microglia/Macrophages Display an Expression Profile Different from M1 and M2 Polarization and Highly Express Gpnmb and Spp1
Frank Szulzewsky et al.
PLOS ONE (2015)
Engineering CAR-T cells: Design concepts
Shivani Srivastava et al.
TRENDS IN IMMUNOLOGY (2015)
Correlation of C-X-C chemokine receptor 2 upregulation with poor prognosis and recurrence in human glioma
Liu Yang et al.
ONCOTARGETS AND THERAPY (2015)
Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling
Marc Zuckermann et al.
NATURE COMMUNICATIONS (2015)
Loss of CX3CR1 increases accumulation of inflammatory monocytes and promotes gliomagenesis
Xi Feng et al.
ONCOTARGET (2015)
Recurrence of glioblastoma after radio-chemotherapy is associated with an angiogenic switch to the CXCL12-CXCR4 pathway
Emeline Tabouret et al.
ONCOTARGET (2015)
Phenotypic Diversity and Plasticity in Circulating Neutrophil Subpopulations in Cancer
Jitka Y. Sagiv et al.
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Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells
Chad M. Toledo et al.
CELL REPORTS (2015)
Microglia versus myeloid cell nomenclature during brain inflammation
Melanie Greter et al.
FRONTIERS IN IMMUNOLOGY (2015)
RNA Sequencing of Tumor-Associated Microglia Reveals Ccl5 as a Stromal Chemokine Critical for Neurofibromatosis-1 Glioma Growth
Anne C. Solga et al.
NEOPLASIA (2015)
Immunosuppressive mechanisms of malignant gliomas: parallels at non-CNS sites
Powell Perng et al.
FRONTIERS IN ONCOLOGY (2015)
RNA-Sequencing Reveals Oligodendrocyte and Neuronal Transcripts in Microglia Relevant to Central Nervous System Disease
Anne C. Solga et al.
GLIA (2015)
CAR-Engineered NK Cells Targeting Wild-Type EGFR and EGFRvIII Enhance Killing of Glioblastoma and Patient-Derived Glioblastoma Stem Cells
Jianfeng Han et al.
SCIENTIFIC REPORTS (2015)
CNS macrophages and peripheral myeloid cells in brain tumours
Rainer Glass et al.
ACTA NEUROPATHOLOGICA (2014)
Inhibition of CXCR7 extends survival following irradiation of brain tumours in mice and rats
M. J. Walters et al.
BRITISH JOURNAL OF CANCER (2014)
Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity
Miranda L. Broz et al.
CANCER CELL (2014)
Neutrophils Promote the Malignant Glioma Phenotype through S100A4
Ji Liang et al.
CLINICAL CANCER RESEARCH (2014)
The role of regulatory T-cells in glioma immunology
Yinn Cher Ooi et al.
CLINICAL NEUROLOGY AND NEUROSURGERY (2014)
Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines
Peter J. Murray et al.
IMMUNITY (2014)
Subpopulations of myeloid-derived suppressor cells impair T cell responses through independent nitric oxide-related pathways
Patrick L. Raber et al.
INTERNATIONAL JOURNAL OF CANCER (2014)
Increased expression of stress inducible protein 1 in glioma-associated microglia/macrophages
Anna Carolina Carvalho da Fonseca et al.
JOURNAL OF NEUROIMMUNOLOGY (2014)
CXCL12 modulation of CXCR4 and CXCR7 activity in human glioblastoma stem-like cells and regulation of the tumor microenvironment
Roberto Wuerth et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2014)
Fractalkine regulation of microglial physiology and consequences on the brain and behavior
Rosa Chiara Paolicelli et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2014)
Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogeny
Martin Guilliams et al.
NATURE REVIEWS IMMUNOLOGY (2014)
Tumor-associated neutrophils (TAN) develop pro-tumorigenic properties during tumor progression
Inbal Mishalian et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2013)
Chemokine receptor trio: CXCR3, CXCR4 and CXCR7 crosstalk via CXCL11 and CXCL12
Anup Kumar Singh et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2013)
A review on CXCR4/CXCL12 axis in oncology: No place to hide
Urszula M. Domanska et al.
EUROPEAN JOURNAL OF CANCER (2013)
The association of pre-treatment neutrophil to lymphocyte ratio with overall survival in patients with glioblastoma multiforme
R. M. Bambury et al.
JOURNAL OF NEURO-ONCOLOGY (2013)
Elevated CD3+ and CD8+ tumor-infiltrating immune cells correlate with prolonged survival in glioblastoma patients despite integrated immunosuppressive mechanisms in the tumor microenvironment and at the systemic level
Justyna Kmiecik et al.
JOURNAL OF NEUROIMMUNOLOGY (2013)
Macrophage plasticity and polarization in tissue repair and remodelling
Alberto Mantovani et al.
JOURNAL OF PATHOLOGY (2013)
Macrophage biology in development, homeostasis and disease
Thomas A. Wynn et al.
NATURE (2013)
CSF-1R inhibition alters macrophage polarization and blocks glioma progression
Stephanie M. Pyonteck et al.
NATURE MEDICINE (2013)
Increase in tumor-associated macrophages after antiangiogenic therapy is associated with poor survival among patients with recurrent glioblastoma
Christine Lu-Emerson et al.
NEURO-ONCOLOGY (2013)
Neutrophil-mediated tumour angiogenesis: Subversion of immune responses to promote tumour growth
Simon Tazzyman et al.
SEMINARS IN CANCER BIOLOGY (2013)
Origin and differentiation of microglia
Florent Ginhoux et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2013)
Macrophages and chemokines as mediators of angiogenesis
Jennifer L. Owen et al.
FRONTIERS IN PHYSIOLOGY (2013)
Natural and induced T regulatory cells in cancer
Dennis O. Adeegbe et al.
FRONTIERS IN IMMUNOLOGY (2013)
The tumor microenvironment: a pitch for multiple players
Giovanna Schiavoni et al.
FRONTIERS IN ONCOLOGY (2013)
Brain dendritic cells: biology and pathology
Paul M. D'Agostino et al.
ACTA NEUROPATHOLOGICA (2012)
IDO Expression in Brain Tumors Increases the Recruitment of Regulatory T Cells and Negatively Impacts Survival
Derek A. Wainwright et al.
CLINICAL CANCER RESEARCH (2012)
Human Tissues Contain CD141hi Cross-Presenting Dendritic Cells with Functional Homology to Mouse CD103+ Nonlymphoid Dendritic Cells
Muzlifah Haniffa et al.
IMMUNITY (2012)
Tumor-Associated Microglia/Macrophages Enhance the Invasion of Glioma Stem-like Cells via TGF-β1 Signaling Pathway
Xian-zong Ye et al.
JOURNAL OF IMMUNOLOGY (2012)
Tumor-secreted SDF-1 promotes glioma invasiveness and TAM tropism toward hypoxia in a murine astrocytoma model
Shu-Chi Wang et al.
LABORATORY INVESTIGATION (2012)
Microglial Stimulation of Glioblastoma Invasion Involves Epidermal Growth Factor Receptor (EGFR) and Colony Stimulating Factor 1 Receptor (CSF-1R) Signaling
Salvatore J. Coniglio et al.
MOLECULAR MEDICINE (2012)
Prognostic Significance of Tumor-Associated Macrophages in Solid Tumor: A Meta-Analysis of the Literature
Qiong-wen Zhang et al.
PLOS ONE (2012)
Bisphosphonates: The first 40 years
R. Graham G. Russell
BONE (2011)
CXCL12/CXCR4 signaling in malignant brain tumors: a potential pharmacological therapeutic target
Mizuhiko Terasaki et al.
BRAIN TUMOR PATHOLOGY (2011)
Chemokine receptor CXCR3 promotes growth of glioma
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CARCINOGENESIS (2011)
Neutrophil Degranulation and Immunosuppression in Patients with GBM: Restoration of Cellular Immune Function by Targeting Arginase I
Trisha R. Sippel et al.
CLINICAL CANCER RESEARCH (2011)
Effector T-Cell Infiltration Positively Impacts Survival of Glioblastoma Patients and Is Impaired by Tumor-Derived TGF-β
Jennifer Lohr et al.
CLINICAL CANCER RESEARCH (2011)
The chemokine network, a newly discovered target in high grade gliomas
U. M. Domanska et al.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2011)
Temozolomide-induced modification of the CXC chemokine network in experimental gliomas
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INTERNATIONAL JOURNAL OF ONCOLOGY (2011)
The chemokine CXCL12 and its receptor CXCR4 promote glioma stem cell-mediated VEGF production and tumour angiogenesis via PI3K/AKT signalling
Yi-fang Ping et al.
JOURNAL OF PATHOLOGY (2011)
Myeloid-derived suppressor cell accumulation and function in patients with newly diagnosed glioblastoma
Baisakhi Raychaudhuri et al.
NEURO-ONCOLOGY (2011)
Thymus-derived rather than tumor-induced regulatory T cells predominate in brain tumors
Derek A. Wainwright et al.
NEURO-ONCOLOGY (2011)
Microglial cell origin and phenotypes in health and disease
Kaoru Saijo et al.
NATURE REVIEWS IMMUNOLOGY (2011)
Cyclic AMP Suppression Is Sufficient to Induce Gliomagenesis in a Mouse Model of Neurofibromatosis-1
Nicole M. Warrington et al.
CANCER RESEARCH (2010)
HER2-Specific T Cells Target Primary Glioblastoma Stem Cells and Induce Regression of Autologous Experimental Tumors
Nabil Ahmed et al.
CLINICAL CANCER RESEARCH (2010)
The chemokine system in cancer biology and therapy
Alberto Mantovani et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2010)
Human glioblastoma tumours and neural cancer stem cells express the chemokine CX3CL1 and its receptor CX3CR1
Marco Erreni et al.
EUROPEAN JOURNAL OF CANCER (2010)
Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice
Mitomu Kioi et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
α4β1 Integrin Mediates the Recruitment of Immature Dendritic Cells across the Blood-Brain Barrier during Experimental Autoimmune Encephalomyelitis
Pooja Jain et al.
JOURNAL OF IMMUNOLOGY (2010)
Prognostic significance and mechanism of Treg infiltration in human brain tumors
Joannes F. M. Jacobs et al.
JOURNAL OF NEUROIMMUNOLOGY (2010)
Chemokines and glioma: Invasion and more
Giuseppe Sciume et al.
JOURNAL OF NEUROIMMUNOLOGY (2010)
CX3CR1/CX3CL1 axis negatively controls glioma cell invasion and is modulated by transforming growth factor-beta1
Giuseppe Sciume et al.
NEURO-ONCOLOGY (2010)
Peptide vaccines prevent tumor growth by activating T cells that respond to native tumor antigens
Kimberly R. Jordan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Development of Monocytes, Macrophages, and Dendritic Cells
Frederic Geissmann et al.
SCIENCE (2010)
Phagocyte partnership during the onset and resolution of inflammation
Oliver Soehnlein et al.
NATURE REVIEWS IMMUNOLOGY (2010)
Role of endothelial progenitors and other bone marrow-derived cells in the development of the tumor vasculature
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ANGIOGENESIS (2009)
The development and function of regulatory T cells
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CELLULAR AND MOLECULAR LIFE SCIENCES (2009)
Analysis of interleukin (IL)-8 expression in human astrocytomas: Associations with IL-6, cyclooxygenase-2, vascular endothelial growth factor, and microvessel morphometry
Vassilis Samaras et al.
HUMAN IMMUNOLOGY (2009)
Tumor-associated macrophage/microglia infiltration in human gliomas is correlated with MCP-3, but not MCP-1
Makoto Okada et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2009)
Cancer-Expanded Myeloid-Derived Suppressor Cells Induce Anergy of NK Cells through Membrane-Bound TGF-beta 1
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JOURNAL OF IMMUNOLOGY (2009)
Induced interleukin-8 expression in gliomas by tumor-associated macrophages
Tse-Ming Hong et al.
JOURNAL OF NEURO-ONCOLOGY (2009)
Incidence and prognostic impact of FoxP3+ regulatory T cells in human gliomas
Amy B. Heimberger et al.
CLINICAL CANCER RESEARCH (2008)
The Interleukin-8 Pathway in Cancer
David J. J. Waugh et al.
CLINICAL CANCER RESEARCH (2008)
Polymorphism in the Microglial Cell-Mobilizing CX3CR1 Gene Is Associated With Survival in Patients With Glioblastoma
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JOURNAL OF CLINICAL ONCOLOGY (2008)
Involvement of nuclear factor-kappa B in bcl-xL-induced interleukin 8 expression in glioblastoma
Chiara Gabellini et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Glial cross-talk by transmembrane chemokines CX3CL1 and CXCL16
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JOURNAL OF NEUROIMMUNOLOGY (2008)
Chemokine production and chemokine receptor expression by human glioma cells: Role of CXCL10 in tumour cell proliferation
Seema V. Maru et al.
JOURNAL OF NEUROIMMUNOLOGY (2008)
CX3CL1 and CX3CR1 in the GL261 murine model of glioma: CX3CR1 deficiency does not impact tumor growth or infiltration of microglia and lymphocytes
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JOURNAL OF NEUROIMMUNOLOGY (2008)
The chemokine CXCL16 induces migration and invasion of glial precursor cells via its receptor CXCR6
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MOLECULAR AND CELLULAR NEUROSCIENCE (2008)
Spatiotemporal differences in CXCL12 expression and cyclic AMP underlie the unique pattern of optic glioma growth in neurofibromatosis type 1
Nicole M. Warrington et al.
CANCER RESEARCH (2007)
CXCR4/CXCL12 axis promotes VEGF-mediated tumor angiogenesis through Akt signaling pathway
Zhongxing Liang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
CD4+CD25+FoxP3+ T-cell infiltration and heme oxygenase-1 expression correlate with tumor grade in human gliomas
Abdeljabar El Andaloussi et al.
JOURNAL OF NEURO-ONCOLOGY (2007)
Neurofibromatosis-1 (Nf1) heterozygous brain microglia elaborate paracrine factors that promote Nf1-deficient astrocyte and glioma growth
Girish C. Daginakatte et al.
HUMAN MOLECULAR GENETICS (2007)
Neurospheres enriched in cancer stem-like cells are highly effective in eliciting a dendritic cell-mediated immune response against malignant gliomas
Serena Pellegatta et al.
CANCER RESEARCH (2006)
Prolongation of survival following depletion of CD4+CD25+ regulatory T cells in mice with experimental brain tumors
Abdeljabar El Andaloussi et al.
JOURNAL OF NEUROSURGERY (2006)
The role of human glioma-infiltrating microglia/macrophages in mediating antitumor immune responses
S. Farzana Hussain et al.
NEURO-ONCOLOGY (2006)
Cancer CXC chemokine networks and tumour angiogenesis
RM Strieter et al.
EUROPEAN JOURNAL OF CANCER (2006)
Increased regulatory T-cell fraction amidst a diminished CD4 compartment explains cellular immune defects in patients with malignant glioma.
PE Fecci et al.
CANCER RESEARCH (2006)
Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host
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CANCER RESEARCH (2006)
Enhanced expression and shedding of the transmembrane chemokine CXCL16 by reactive astrocytes and glioma cells
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JOURNAL OF NEUROCHEMISTRY (2005)
Defining the antigen-specific T-Cell response to vaccination and poly(I:C)/TLR3 signaling -: Evidence of enhanced primary and memory CD8 T-Cell responses and antitumor immunity
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JOURNAL OF IMMUNOTHERAPY (2005)
The contribution of bone marrow-derived cells to the tumor vasculature in neuroblastoma is matrix metalloproteinase-9 dependent
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CANCER RESEARCH (2005)
The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis
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NEURO-ONCOLOGY (2005)
Induction of a CD4+ T regulatory type 1 response by cyclooxygenase-2-overexpressing glioma
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JOURNAL OF IMMUNOLOGY (2004)
Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL
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NATURE (2003)
IL-8 directly enhanced endothelial cell survival, proliferation, and matrix metalloproteinases production and regulated angiogenesis
AH Li et al.
JOURNAL OF IMMUNOLOGY (2003)
Cross-talk between tumor cells and neutrophils through the Fas (APO-1, CD95)/FasL system: human glioma cells enhance cell viability and stimulate cytokine production in neutrophils
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Tumour escape from immune surveillance through dendritic cell inactivation
AP Vicari et al.
SEMINARS IN CANCER BIOLOGY (2002)
Down-regulation of Fas-L in glioma cells by ribozyme reduces cell apoptosis, tumour-infiltrating cells, and liver damage but accelerates tumour formation in nude mice
CC Chio et al.
BRITISH JOURNAL OF CANCER (2001)
CXC chemokine receptor 4 expression and function in human astroglioma cells
JW Oh et al.
JOURNAL OF IMMUNOLOGY (2001)
Glioma cell invasion: regulation of metalloproteinase activity by TGF-beta
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JOURNAL OF NEURO-ONCOLOGY (2001)
The CXC chemokine receptor 2, CXCR2, is the putative receptor for ELR+ CXC chemokine-induced angiogenic activity
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JOURNAL OF IMMUNOLOGY (2000)