4.7 Review

Antidiabetic Drugs in the Treatment of Alzheimer's Disease

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Biochemistry & Molecular Biology

Role of polyphenols in combating Type 2 Diabetes and insulin resistance

Moyad Shahwan et al.

Summary: Compromised carbohydrate metabolism leading to hyperglycemia is the primary metabolic disorder of non-insulin-dependent diabetes mellitus. Polyphenolic compounds play an important role in regulating insulin resistance and carbohydrate metabolism through inhibiting key enzymes and activating specific pathways to control blood glucose levels.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022)

Review Biochemistry & Molecular Biology

Alzheimer's Disease as Type 3 Diabetes: Common Pathophysiological Mechanisms between Alzheimer's Disease and Type 2 Diabetes

Michalis Michailidis et al.

Summary: This review article discusses the shared pathophysiological connections between Alzheimer's disease (AD) and type 2 diabetes mellitus (T2DM), emphasizing the role of insulin in the brain and the mechanistic interplay between the two diseases. The findings highlight the need for routine evaluation and treatment of cognitive impairment in T2DM patients and the evaluation of insulin levels or T2DM in AD patients. The hypothesis of AD as a type 3 diabetes is strongly supported.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Article Endocrinology & Metabolism

3. Prevention or Delay of Type 2 Diabetes: Standards of Medical Care in Diabetes-2021

Summary: The American Diabetes Association's Standards of Medical Care in Diabetes consist of clinical practice recommendations, components of diabetes care, and tools for evaluating quality of care. The committee is responsible for updating the standards annually, and monitoring for the development of type 2 diabetes in those with prediabetes is suggested. Screening for prediabetes in high-risk patients is recommended as it provides an effective means of preventing type 2 diabetes.

DIABETES CARE (2021)

Article Clinical Neurology

The Rate of Decrease in Brain Perfusion in Progressive Supranuclear Palsy and Corticobasal Syndrome May Be Impacted by Glycemic Variability-A Pilot Study

Piotr Alster et al.

Summary: In this study, higher glycemic variability in PSP and CBS patients was associated with more severe hypoperfusion in certain brain regions, potentially impacting the rate of cognitive deterioration.

FRONTIERS IN NEUROLOGY (2021)

Article Medicine, General & Internal

The PRISMA 2020 statement: An updated guideline for reporting systematic reviews

Matthew J. Page et al.

Summary: The article introduces PRISMA 2020, an updated reporting guideline for systematic reviews and meta-analyses.

PLOS MEDICINE (2021)

Review Geriatrics & Gerontology

Multi-Loop Model of Alzheimer Disease: An Integrated Perspective on the Wnt/GSK3β, α-Synuclein, and Type 3 Diabetes Hypotheses

Nicholas G. Norwitz et al.

FRONTIERS IN AGING NEUROSCIENCE (2019)

Review Biochemistry & Molecular Biology

History and progress of hypotheses and clinical trials for Alzheimer's disease

Pei-Pei Liu et al.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2019)

Article Pharmacology & Pharmacy

Novel dual incretin agonist peptide with antidiabetic and neuroprotective potential

N. M. Pathak et al.

BIOCHEMICAL PHARMACOLOGY (2018)

Review Endocrinology & Metabolism

Cognitive decline and dementia in diabetes mellitus: mechanisms and clinical implications

Geert Jan Biessels et al.

NATURE REVIEWS ENDOCRINOLOGY (2018)

Review Clinical Neurology

Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums

Steven E. Arnold et al.

NATURE REVIEWS NEUROLOGY (2018)

Review Endocrinology & Metabolism

Antidiabetic Drugs in Alzheimer's Disease: Mechanisms of Action and Future Perspectives

Grazia Daniela Femminella et al.

JOURNAL OF DIABETES RESEARCH (2017)

Article Endocrinology & Metabolism

Glucose Peaks and the Risk of Dementia and 20-Year Cognitive Decline

Andreea M. Rawlings et al.

DIABETES CARE (2017)

Review Chemistry, Medicinal

Targeting Insulin Signaling for the Treatment of Alzheimer's Disease

Yanxing Chen et al.

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2016)

Article Clinical Neurology

APOE2 Eases Cognitive Decline during Aging: Clinical and Preclinical Evaluations

Mitsuru Shinohara et al.

ANNALS OF NEUROLOGY (2016)

Article Biochemistry & Molecular Biology

PPARγ agonist pioglitazone improves cerebellar dysfunction at pre-Aβ deposition stage in APPswe/PS1dE9 Alzheimer's disease model mice

Junya Toba et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)

Article Endocrinology & Metabolism

Rapid transport within cerebral perivascular spaces underlies widespread tracer distribution in the brain after intranasal administration

Jeffrey J. Lochhead et al.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2015)

Article Clinical Neurology

Evaluation of neuroprotective effect of glucagon-like peptide 1 analogs using neuroimaging

Grazia D. Femminella et al.

ALZHEIMERS & DEMENTIA (2014)

Article Biochemistry & Molecular Biology

Insulin, incretins and other growth factors as potential novel treatments for Alzheimer's and Parkinson's diseases

Christian Hoelscher

BIOCHEMICAL SOCIETY TRANSACTIONS (2014)

Article Endocrinology & Metabolism

Insulin Action in Brain Regulates Systemic Metabolism and Brain Function

Andre Kleinridders et al.

DIABETES (2014)

Article Neurosciences

Long-Term Metformin Usage and Cognitive Function among Older Adults with Diabetes

Tze Pin Ng et al.

JOURNAL OF ALZHEIMERS DISEASE (2014)

Article Infectious Diseases

Sulphonylurea Usage in Melioidosis Is Associated with Severe Disease and Suppressed Immune Response

Xiang Liu et al.

PLOS NEGLECTED TROPICAL DISEASES (2014)

Article Clinical Neurology

Glucagon-like peptide-1 (GLP-1) mimetics: a new treatment for Alzheimer's disease?

Natalia Garcia-Casares et al.

REVISTA DE NEUROLOGIA (2014)

Article Endocrinology & Metabolism

Increased Risk of Cognitive Impairment in Patients With Diabetes Is Associated With Metformin

Eileen M. Moore et al.

DIABETES CARE (2013)

Review Pharmacology & Pharmacy

Intranasal insulin therapy for cognitive impairment and neurodegeneration: current state of the art

Suzanne M. de la Monte

EXPERT OPINION ON DRUG DELIVERY (2013)

Article Pharmacology & Pharmacy

Vildagliptin: an anti-diabetes agent ameliorates cognitive deficits and pathology observed in streptozotocin-induced Alzheimer's disease

Jayasankar Kosaraju et al.

JOURNAL OF PHARMACY AND PHARMACOLOGY (2013)

Review Clinical Neurology

Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy

Chia-Chan Liu et al.

NATURE REVIEWS NEUROLOGY (2013)

Article Endocrinology & Metabolism

Risk score for prediction of 10 year dementia risk in individuals with type 2 diabetes: a cohort study

Lieza G. Exalto et al.

LANCET DIABETES & ENDOCRINOLOGY (2013)

Article Geriatrics & Gerontology

Metformin, Other Antidiabetic Drugs, and Risk of Alzheimer's Disease: A Population-Based Case-Control Study

Patrick Imfeld et al.

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2012)

Review Neurosciences

The many faces of insulin-like peptide signalling in the brain

Ana M. Fernandez et al.

NATURE REVIEWS NEUROSCIENCE (2012)

Article Public, Environmental & Occupational Health

Risk of Alzheimer's Disease in Relation to Diabetes: A Population-Based Cohort Study

Kai-Chen Wang et al.

NEUROEPIDEMIOLOGY (2012)

Article Geriatrics & Gerontology

Efficacy of PPAR-γ agonist pioglitazone in mild Alzheimer disease

Tomohiko Sato et al.

NEUROBIOLOGY OF AGING (2011)

Article Multidisciplinary Sciences

Biguanide metformin acts on tau phosphorylation via mTOR/protein phosphatase 2A (PP2A) signaling

Eva Kickstein et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Editorial Material Pharmacology & Pharmacy

Behind the rosiglitazone controversy

Bernard M. Y. Cheung

EXPERT REVIEW OF CLINICAL PHARMACOLOGY (2010)

Article Medicine, General & Internal

Role of the incretin pathway in the pathogenesis of type 2 diabetes mellitus

J. S. FREEMAN

CLEVELAND CLINIC JOURNAL OF MEDICINE (2009)

Review Biochemistry & Molecular Biology

Distinct modulation of voltage-gated and ligand-gated Ca2+ currents by PPAR-γ agonists in cultured hippocampal neurons

Tristano Pancani et al.

JOURNAL OF NEUROCHEMISTRY (2009)

Letter Geriatrics & Gerontology

PIOGLITAZONE IMPROVED COGNITION IN A PILOT STUDY ON PATIENTS WITH ALZHEIMER'S DISEASE AND MILD COGNITIVE IMPAIRMENT WITH DIABETES MELLITUS

Giuseppe Bellelli et al.

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2009)

Review Medicine, Research & Experimental

PPARs in Alzheimer's Disease

Markus P. Kummer et al.

PPAR RESEARCH (2008)

Article Clinical Neurology

Therapeutic use of agonists of the nuclear receptor PPARγ in Alzheimer's disease

Gary Landreth

CURRENT ALZHEIMER RESEARCH (2007)

Article Clinical Neurology

Relation of diabetes to mild cognitive impairment

Jose A. Luchsinger et al.

ARCHIVES OF NEUROLOGY (2007)

Review Pharmacology & Pharmacy

Mechanisms of action of glucagon-like peptide 1 in the pancreas

Maire E. Doyle et al.

PHARMACOLOGY & THERAPEUTICS (2007)

Article Clinical Neurology

Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function

Z Arvanitakis et al.

ARCHIVES OF NEUROLOGY (2004)