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CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS (2013)
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CURRENT MEDICINAL CHEMISTRY (2013)
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2013)
Arginine modified PAMAM dendrimer for interferon beta gene delivery to malignant glioma
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INTERNATIONAL JOURNAL OF PHARMACEUTICS (2013)
PEGylated polylysine dendrimers increase lymphatic exposure to doxorubicin when compared to PEGylated liposomal and solution formulations of doxorubicin
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Combination of paclitaxel thermal gel depot with temozolomide and radiotherapy significantly prolongs survival in an experimental rodent glioma model
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Optimization of the route of platinum drugs administration to optimize the concomitant treatment with radiotherapy for glioblastoma implanted in the Fischer rat brain
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NATURE MEDICINE (2013)
Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface
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NATURE NANOTECHNOLOGY (2013)
Effects of Particle Size and Surface Modification on Cellular Uptake and Biodistribution of Polymeric Nanoparticles for Drug Delivery
Sneha A. Kulkarni et al.
PHARMACEUTICAL RESEARCH (2013)
Transcytosis and brain uptake of transferrin-containing nanoparticles by tuning avidity to transferrin receptor
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Spherical Nucleic Acid Nanoparticle Conjugates as an RNAi-Based Therapy for Glioblastoma
Samuel A. Jensen et al.
SCIENCE TRANSLATIONAL MEDICINE (2013)
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FRONTIERS IN PHARMACOLOGY (2013)
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FRONTIERS IN PHARMACOLOGY (2013)
In vivo SELEX for Identification of Brain-penetrating Aptamers
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MOLECULAR THERAPY-NUCLEIC ACIDS (2013)
Receptor-Mediated Delivery of Magnetic Nanoparticles across the Blood-Brain Barrier
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ACS NANO (2012)
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The transport of non-surfactant based paclitaxel loaded magnetic nanoparticles across the blood brain barrier in a rat model
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BIOMATERIALS (2012)
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A Novel Liposome Surface Modification Agent that Prolongs Blood Circulation and Retains Surface Ligand Reactivity
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William M. Pardridge
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Can leptin-derived sequence-modified nanoparticles be suitable tools for brain delivery?
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William T. Phillips et al.
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Inhibition of C6 glioma in vivo by combination chemotherapy of implantation of polymer wafer and intracarotid perfusion of transferrin-decorated nanoparticles
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ONCOLOGY REPORTS (2012)
A Dense Poly(Ethylene Glycol) Coating Improves Penetration of Large Polymeric Nanoparticles Within Brain Tissue
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SCIENCE TRANSLATIONAL MEDICINE (2012)
Four types of inorganic nanoparticles stimulate the inflammatory reaction in brain microglia and damage neurons in vitro
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TOXICOLOGY LETTERS (2012)
IMPROVED ANTI-TUMOR EFFECT OF LIPOSOMAL DOXORUBICIN AFTER TARGETED BLOOD-BRAIN BARRIER DISRUPTION BY MRI-GUIDED FOCUSED ULTRASOUND IN RAT GLIOMA
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ULTRASOUND IN MEDICINE AND BIOLOGY (2012)
Translocating the blood-brain barrier using electrostatics
Marta M. B. Ribeiro et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2012)
Magnetic nanoparticles: an emerging technology for malignant brain tumor imaging and therapy
Mamta Wankhede et al.
EXPERT REVIEW OF CLINICAL PHARMACOLOGY (2012)
Neurotoxicity of Silica Nanoparticles: Brain Localization and Dopaminergic Neurons Damage Pathways
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ACS NANO (2011)
The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect
Jun Fang et al.
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RGD-Modified PEG-PAMAM-DOX Conjugate: In Vitro and In Vivo Targeting to Both Tumor Neovascular Endothelial Cells and Tumor Cells
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The treatment of Glioblastoma Xenografts by surfactant conjugated dendritic nanoconjugates
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BIOMATERIALS (2011)
Nanoparticles and Neurotoxicity
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Efficacy and safety of intratumoral thermotherapy using magnetic iron-oxide nanoparticles combined with external beam radiotherapy on patients with recurrent glioblastoma multiforme
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JOURNAL OF NEURO-ONCOLOGY (2011)
Adenosine Receptor Signaling Modulates Permeability of the Blood-Brain Barrier
Aaron J. Carman et al.
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Safety and maximum tolerated dose of superselective intraarterial cerebral infusion of bevacizumab after osmotic blood-brain barrier disruption for recurrent malignant glioma Clinical article
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Surface Characteristics of Nanoparticles Determine Their Intracellular Fate in and Processing by Human Blood-Brain Barrier Endothelial Cells In Vitro
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MOLECULAR THERAPY (2011)
Conjugation of functionalized gadolinium metallofullerenes with IL-13 peptides for targeting and imaging glial tumors
Helen L. Fillmore et al.
NANOMEDICINE (2011)
Microglial activation, recruitment and phagocytosis as linked phenomena in ferric oxide nanoparticle exposure
Yun Wang et al.
TOXICOLOGY LETTERS (2011)
Nanoparticle-based theranostic agents
Jin Xie et al.
ADVANCED DRUG DELIVERY REVIEWS (2010)
Leptin-derived peptide, a targeting ligand for mouse brain-derived endothelial cells via macropinocytosis
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Partly PEGylated polyamidoamine dendrimer for tumor-selective targeting of doxorubicin: The effects of PEGylation degree and drug conjugation style
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BIOMATERIALS (2010)
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Filipa Lourenco Cardoso et al.
BRAIN RESEARCH REVIEWS (2010)
Selective targeting of a TNFR decoy receptor pharmaceutical to the primate brain as a receptor-specific IgG fusion protein
Ruben J. Boado et al.
JOURNAL OF BIOTECHNOLOGY (2010)
Targeted Imaging and Therapy of Brain Cancer Using Theranostic Nanoparticles
Mahaveer Swaroop Bhojani et al.
MOLECULAR PHARMACEUTICS (2010)
Peptide-Conjugated PAMAM for Targeted Doxorubicin Delivery to Transferrin Receptor Overexpressed Tumors
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MOLECULAR PHARMACEUTICS (2010)
Structure and function of the blood-brain barrier
N. Joan Abbott et al.
NEUROBIOLOGY OF DISEASE (2010)
Specific Visualization of Glioma Cells in Living Low-Grade Tumor Tissue
Sven R. Kantelhardt et al.
PLOS ONE (2010)
Magnetic resonance monitoring of focused ultrasound/magnetic nanoparticle targeting delivery of therapeutic agents to the brain
Hao-Li Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Targeted drug delivery across the blood-brain barrier using ultrasound technique
Cheri X. Deng
THERAPEUTIC DELIVERY (2010)
RNOP-09: Pegylated liposomal doxorubicine and prolonged temozolomide in addition to radiotherapy in newly diagnosed glioblastoma - a phase II study
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BMC CANCER (2009)
Antitumor effects of polysorbate-80 coated gemcitabine polybutylcyanoacrylate nanoparticles in vitro and its pharmacodynamics in vivo on C6 glioma cells of a brain tumor model
Chun-Xia Wang et al.
BRAIN RESEARCH (2009)
Transferrin- and transferrin-receptor-antibody-modified nanoparticles enable drug delivery across the blood-brain barrier (BBB)
Karsten Ulbrich et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2009)
MR imaging of tumor angiogenesis using sterically stabilized Gd-DTPA liposomes targeted to CD105
Zhang Dong et al.
EUROPEAN JOURNAL OF RADIOLOGY (2009)
Tumor-Targeted Quantum Dots Can Help Surgeons Find Tumor Boundaries
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IEEE TRANSACTIONS ON NANOBIOSCIENCE (2009)
Albumin nanoparticles targeted with Apo E enter the CNS by transcytosis and are delivered to neurones
Anja Zensi et al.
JOURNAL OF CONTROLLED RELEASE (2009)
Dual-Targeting Topotecan Liposomes Modified with Tamoxifen and Wheat Germ Agglutinin Significantly Improve Drug Transport across the Blood-Brain Barrier and Survival of Brain Tumor-Bearing Animals
Ju Du et al.
MOLECULAR PHARMACEUTICS (2009)
Growth Inhibition Against Intracranial C6 Glioma Cells by Stereotactic Delivery of BCNU by Controlled Release from poly(D,L-lactic acid) Nanoparticles
ChunSheng Kang et al.
TECHNOLOGY IN CANCER RESEARCH & TREATMENT (2009)
Liposomes and nanoparticles: nanosized vehicles for drug delivery in cancer
Yogeshkumar Malam et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2009)
CNS Delivery Via Adsorptive Transcytosis
Francoise Herve et al.
AAPS JOURNAL (2008)
Quantum Dots Bearing Lectin-Functionalized Nanoparticles as a Platform for In Vivo Brain Imaging
Xiaoling Gao et al.
BIOCONJUGATE CHEMISTRY (2008)
Intranasal delivery bypasses the blood-brain barrier to target therapeutic agents to the central nervous system and treat neurodegenerative disease
Leah R. Hanson et al.
BMC NEUROSCIENCE (2008)
Biodistribution of colloidal gold nanoparticles after intravenous administration: Effect of particle size
Ganeshchandra Sonavane et al.
COLLOIDS AND SURFACES B-BIOINTERFACES (2008)
Adenosine as a neuromodulator in neurological diseases
Detlev Boison
CURRENT OPINION IN PHARMACOLOGY (2008)
Methotrexate loaded polyether-copolyester dendrimers for the treatment of gliomas: Enhanced efficacy and intratumoral transport capability
Renu Singh Dhanikula et al.
MOLECULAR PHARMACEUTICS (2008)
Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats
Michelle Longmire et al.
NANOMEDICINE (2008)
Effect of focused ultrasound applied with an ultrasound contrast agent on the tight junctional integrity of the brain microvascular endothelium
Nickolai Sheikov et al.
ULTRASOUND IN MEDICINE AND BIOLOGY (2008)
Receptor-targeted quantum dots: fluorescent probes for brain tumor diagnosis
Jingjing Wang et al.
JOURNAL OF BIOMEDICAL OPTICS (2007)
Calcium-activated potassium channels mediated blood-brain tumor barrier opening in a rat metastatic brain tumor model
Jinwei Hu et al.
MOLECULAR CANCER (2007)
Quantum dots are phagocytized by macrophages and colocalize with experimental gliomas
Heather Jackson et al.
NEUROSURGERY (2007)
Blood-brain barrier transport of therapeutics via receptor-mediation
Angela R. Jones et al.
PHARMACEUTICAL RESEARCH (2007)
Vascular targeted nanoparticles for imaging and treatment of brain tumors
G. Ramachandra Reddy et al.
CLINICAL CANCER RESEARCH (2006)
Molecular Trojan horses for blood-brain barrier drug delivery
William M. Pardridge
CURRENT OPINION IN PHARMACOLOGY (2006)
In vitro and in vivo imaging studies of a new endohedral metallofullerene nanoparticle
Panos P. Fatouros et al.
RADIOLOGY (2006)
Phase II trial of intravenous lobradimil and carboplatin in childhood brain tumors: a report from the Children's Oncology Group
K. Warren et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2006)
Translocation of inhaled ultrafine manganese oxide particles to the central nervous system
Alison Elder et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2006)
Covalent linkage of apolipoprotein E to albumin nanoparticles strongly enhances drug transport into the brain
K. Michaelis et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
In vivo diffusion analysis with quantum dots and dextrans predicts the width of brain extracellular space
RG Thorne et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Influence of particle size on transport of methotrexate across blood brain barrier by polysorbate 80-coated polybutylcyanoacrylate nanoparticles
KP Gao et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2006)
Astrocyte-endothelial interactions at the blood-brain barrier
NJ Abbott et al.
NATURE REVIEWS NEUROSCIENCE (2006)
Enhanced chemotherapy delivery by intraarterial infusion and blood-brain barrier disruption in malignant brain tumors: The sherbrooke experience
D Fortin et al.
CANCER (2005)
The blood-brain barrier/neurovascular unit in health and disease
BT Hawkins et al.
PHARMACOLOGICAL REVIEWS (2005)
Validation of the transferrin receptor for drug targeting to brain capillary endothelial cells in vitro
CC Visser et al.
JOURNAL OF DRUG TARGETING (2004)
Cellular mechanisms of the blood-brain barrier opening induced by ultrasound in presence of microbubbles
N Sheikov et al.
ULTRASOUND IN MEDICINE AND BIOLOGY (2004)
Phase 2 study of temozolomide and Caelyx in patients with recurrent glioblastoma multiforme
SL Chua et al.
NEURO-ONCOLOGY (2004)
Targeting anti-transferrin receptor antibody (OX26) and OX26-conjugated liposomes to brain capillary endothelial cells using in situ perfusion
T Gosk et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2004)
The blood-brain barrier: an overview - Structure, regulation, and clinical implications
P Ballabh et al.
NEUROBIOLOGY OF DISEASE (2004)
Nanomaterials based on phosphorus dendrimers
AM Caminade et al.
ACCOUNTS OF CHEMICAL RESEARCH (2004)
Nanoparticle surface charges alter blood-brain barrier integrity and permeability
PR Lockman et al.
JOURNAL OF DRUG TARGETING (2004)
Dendrimers as potential drug carriers; encapsulation of acidic hydrophobes within water soluble PAMAM derivatives
AE Beezer et al.
TETRAHEDRON (2003)
In vivo knockdown of gene expression in brain cancer with intravenous RNAi in adutt rats
Y Zhang et al.
JOURNAL OF GENE MEDICINE (2003)
Poly(amidoamine) (PAMAM) dendrimers: from biomimicry to drug delivery and biomedical applications
R Esfand et al.
DRUG DISCOVERY TODAY (2001)
High intratumoural accumulation of stealth® liposomal doxorubicin (Caelyx®) in glioblastomas and in metastatic brain tumours
MI Koukourakis et al.
BRITISH JOURNAL OF CANCER (2000)