期刊
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
卷 23, 期 9, 页码 -出版社
MDPI
DOI: 10.3390/ijms23094737
关键词
graphene; graphene oxide; caries; pulp infection; periodontitis; osseointegration
资金
- National Natural Science Foundation [32171354]
- Fundamental Research Funds for Central Universities
- Youth Innovation Promotion Association of Chinese Academy of Sciences
Oral diseases are a global public health problem that cause significant financial burdens. Graphene nanomaterials have unique properties that make them suitable for dental therapies, such as restoration, drug delivery, and tissue regeneration. They can also adapt to the complex oral microenvironment.
Oral diseases present a global public health problem that imposes heavy financial burdens on individuals and health-care systems. Most oral health conditions can be treated in their early stage. Even if the early symptoms of oral diseases do not seem to cause significant discomfort, prompt treatment is essential for preventing their progression. Biomaterials with superior properties enable dental therapies with applications in restoration, therapeutic drug/protein delivery, and tissue regeneration. Graphene nanomaterials have many unique mechanical and physiochemical properties and can respond to the complex oral microenvironment, which includes oral microbiota colonization and high masticatory force. Research on graphene nanomaterials in dentistry, especially in caries, periodontitis therapy, and implant coatings, is progressing rapidly. Here, we review the development of graphene and its derivatives for dental disease therapy.
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