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ISCIENCE (2019)
Unbalanced Vitreous Levels of Osteoprotegerin, RANKL, RANK, and TRAIL in Proliferative Diabetic Retinopathy
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Fas and Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Are Closely Linked to the Levels of Glycated and Fetal Hemoglobin in Patients with Diabetes Mellitus
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Tumour necrosis factor-related apoptosis-inducing ligand expression in patients with diabetic nephropathy
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TRAIL reduces impaired glucose tolerance and NAFLD in the high-fat diet fed mouse
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CLINICAL SCIENCE (2018)
Trail (TNF-related apoptosis-inducing ligand) induces an inflammatory response in human adipocytes
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Elevated Markers of Death Receptor-Activated Apoptosis are Associated with Increased Risk for Development of Diabetes and Cardiovascular Disease
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EBIOMEDICINE (2017)
Non-alcoholic fatty liver disease, vascular inflammation and insulin resistance are exacerbated by TRAIL deletion in mice
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SCIENTIFIC REPORTS (2017)
The Autophagy Machinery Controls Cell Death Switching between Apoptosis and Necroptosis
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DEVELOPMENTAL CELL (2016)
Redox signaling and oxidative stress: Cross talk with TNF-related apoptosis inducing ligand activity
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INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2016)
Insulin resistance and sarcopenia: mechanistic links between common co-morbidities
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JOURNAL OF ENDOCRINOLOGY (2016)
Dyslipidemia and Diabetes Increase the OPG/TRAIL Ratio in the Cardiovascular System
Barbara Toffoli et al.
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TRAIL (TNF-related apoptosis-inducing ligand) inhibits human adipocyte differentiation via caspase-mediated downregulation of adipogenic transcription factors
Verena Zoller et al.
CELL DEATH & DISEASE (2016)
Roles and Clinical Applications of OPG and TRAIL as Biomarkers in Cardiovascular Disease
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BIOMED RESEARCH INTERNATIONAL (2016)
Serum TRAIL levels increase shortly after insulin therapy and metabolic stabilization in children with type 1 diabetes mellitus
Gianluca Tornese et al.
ACTA DIABETOLOGICA (2015)
Low serum TNF-related apoptosis-inducing ligand (TRAIL) levels are associated with acute ischemic stroke severity
Yang Ho Kang et al.
ATHEROSCLEROSIS (2015)
TNF-related apoptosis-inducing ligand promotes human preadipocyte proliferation via ERK1/2 activation
Jan-Bernd Funcke et al.
FASEB JOURNAL (2015)
TRAIL receptor deletion in mice suppresses the inflammation of nutrient excess
Leila Idrissova et al.
JOURNAL OF HEPATOLOGY (2015)
Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) Promotes Angiogenesis and Ischemia-Induced Neovascularization Via NADPH Oxidase 4 (NOX4) and Nitric Oxide-Dependent Mechanisms
Belinda Ann Di Bartolo et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2015)
TRAIL Modulates the Immune System and Protects against the Development of Diabetes
Fleur Bossi et al.
JOURNAL OF IMMUNOLOGY RESEARCH (2015)
The levels of circulating TRAIL at the onset of type 1 diabetes are markedly decreased in patients with ketoacidosis and with the highest insulin requirement
Gianluca Tornese et al.
ACTA DIABETOLOGICA (2014)
Circulating level of TRAIL concentration is positively associated with endothelial function and increased by diabetic therapy in the newly diagnosed type 2 diabetic patients
Guangda Xiang et al.
CLINICAL ENDOCRINOLOGY (2014)
Does DcR1 (TNF-related apoptosis-inducing-ligand Receptor 3) have any role in human AMD pathogenesis?
Akshay Anand et al.
SCIENTIFIC REPORTS (2014)
Ocular Disease, Knowledge and Technology Applications in Patients With Diabetes
Jennifer Threatt et al.
AMERICAN JOURNAL OF THE MEDICAL SCIENCES (2013)
Non-canonical kinase signaling by the death ligand TRAIL in cancer cells: discord in the death receptor family
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CELL DEATH AND DIFFERENTIATION (2013)
Association of Soluble Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) with Central Adiposity and Low-Density Lipoprotein Cholesterol
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PLOS ONE (2013)
TRAIL-Deficiency Accelerates Vascular Calcification in Atherosclerosis via Modulation of RANKL
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PLOS ONE (2013)
On the TRAIL of obesity and diabetes
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TRENDS IN ENDOCRINOLOGY AND METABOLISM (2013)
TRAIL (TNF-related apoptosis-inducing ligand) regulates adipocyte metabolism by caspase-mediated cleavage of PPARgamma
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CELL DEATH & DISEASE (2013)
Association of circulating sTRAIL and high-sensitivity CRP with type 2 diabetic nephropathy and foot ulcers
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MEDICAL SCIENCE MONITOR (2013)
Attenuation of TNFSF10/TRAIL-induced apoptosis by an autophagic survival pathway involving TRAF2-and RIPK1/RIP1-mediated MAPK8/JNK activation
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AUTOPHAGY (2012)
TRAIL induces necroptosis involving RIPK1/RIPK3-dependent PARP-1 activation
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CELL DEATH AND DIFFERENTIATION (2012)
TNF-related apoptosis-inducing ligand significantly attenuates metabolic abnormalities in high-fat-fed mice reducing adiposity and systemic inflammation
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CLINICAL SCIENCE (2012)
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CURRENT PHARMACEUTICAL DESIGN (2012)
Circulating soluble tumor necrosis factor related apoptosis inducing-ligand (TRAIL) is decreased in type-2 newly diagnosed, non-drug using diabetic patients
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DIABETES RESEARCH AND CLINICAL PRACTICE (2012)
Association of soluble tumour necrosis factor-related apoptosis-inducing ligand levels with coronary plaque burden and composition
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HEART (2012)
TRAIL shows potential cardioprotective activity
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INVESTIGATIONAL NEW DRUGS (2012)
Association of tumor necrosis factor-related apoptosis-inducing ligand with total and cardiovascular mortality in older adults
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ATHEROSCLEROSIS (2011)
Association of serum TRAIL levels with atherosclerosis in patients with type 2 diabetes mellitus
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DIABETES RESEARCH AND CLINICAL PRACTICE (2011)
Decreased levels of soluble TNF-related apoptosis-inducing ligand (TRAIL) in the conjunctival sac fluid of patients with diabetes affected by proliferative retinopathy
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JOURNAL OF CLINICAL INVESTIGATION (2011)
Similar to adiponectin, serum levels of osteoprotegerin are associated with obesity in healthy subjects
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Metalloproteinase 2 cleaves in vitro recombinant TRAIL: Potential implications for the decreased serum levels of TRAIL after acute myocardial infarction
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ATHEROSCLEROSIS (2010)
Treatment With Recombinant Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Alleviates the Severity of Streptozotocin-Induced Diabetes
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DIABETES (2010)
Systemic Delivery of TNF-Related Apoptosis-Inducing Ligand (TRAIL) Elevates Levels of Tissue Inhibitor of Metalloproteinase-1 (TIMP-1) and Prevents Type 1 Diabetes in Nonobese Diabetic Mice
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TRAIL-Deficient Mice Exhibit Delayed Regression of Retinal Neovascularization
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Role of full-length osteoprotegerin in tumor cell biology
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Adenovirus-Mediated TRAIL Gene (Ad5hTRAIL) Delivery into Pancreatic Islets Prolongs Normoglycemia in Streptozotocin-Induced Diabetic Rats
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Lipid rafts and nonrafts mediate tumor necrosis factor-related apoptosis-inducing ligand-induced apoptotic and nonapoptotic signals in non-small cell lung carcinoma cells
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CANCER RESEARCH (2007)
Systemic tumor necrosis factor-related apoptosis-inducing ligand delivery shows antiatherosclerotic activity in apolipoprotein E-null diabetic mice
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CIRCULATION (2006)
The involvement of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in atherosclerosis
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JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2005)
Tumor necrosis factor-related apoptosis-inducing ligand and CD56 expression in patients with type 1 diabetes mellitus
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PANCREAS (2005)
TRAIL promotes the survival, migration and proliferation of vascular smooth muscle cells
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CELLULAR AND MOLECULAR LIFE SCIENCES (2004)
Critical roles of tumor necrosis factor-related apoptosis-inducing ligand in type 1 diabetes
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DIABETES (2003)
Blockade of tumor necrosis factor-related apoptosis-inducing ligand exacerbates type 1 diabetes in NOD mice
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DIABETES (2003)
Tumour necrosis factor-related apoptosis-inducing ligand sequentially activates pro-survival and pro-apoptotic pathways in SK-N-MC neuronal cells
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JOURNAL OF NEUROCHEMISTRY (2003)
TRAIL promotes the survival and proliferation of primary human vascular endothelial cells by activating the Akt and ERK pathways
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CIRCULATION (2003)
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) sequentially upregulates nitric oxide and prostanoid production in primary human endothelial cells
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Defective thymocyte apoptosis and accelerated autoimmune diseases in TRAIL-/- mice
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The role of apoptosis in age-related macular degeneration
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Death ligand TRAIL induces no apoptosis but inhibits activation of human (auto)antigen-specific T cells
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JOURNAL OF IMMUNOLOGY (2002)
Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice
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JOURNAL OF IMMUNOLOGY (2002)
Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development
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JOURNAL OF EXPERIMENTAL MEDICINE (2002)
The molecular architecture of the TNF superfamily
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