☆ 4.7 Review

Tumor Microenvironment of Hepatocellular Carcinoma: Challenges and Opportunities for New Treatment Options

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

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Lenvatinib versus sorafenib in first-line treatment of patients with unresectable hepatocellular carcinoma: a randomised phase 3 non-inferiority trial

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Ten years of sorafenib in hepatocellular carcinoma: Are there any predictive and/or prognostic markers?

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IL-6 Trans-Signaling Is Essential for the Development of Hepatocellular Carcinoma in Mice

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A Liver Capsular Network of Monocyte-Derived Macrophages Restricts Hepatic Dissemination of Intraperitoneal Bacteria by Neutrophil Recruitment

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Deletion of interleukin-6 in monocytes/macrophages suppresses the initiation of hepatocellular carcinoma in mice

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Kupffer Cells Promote Hepatic Steatosis Via Interleukin-1β-Dependent Suppression of Peroxisome Proliferator-Activated Receptor α Activity

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Transforming Growth Factor-Beta Induces Senescence in Hepatocellular Carcinoma Cells and Inhibits Tumor Growth

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Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

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Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer.

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Myeloid Derived Suppressor Cells Inhibit Natural Killer Cells in Patients with Hepatocellular Carcinoma via the NKp30 Receptor

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High tumor-infiltrating macrophage density predicts poor prognosis in patients with primary hepatocellular carcinoma after resection

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Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial

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FDA approves sorafenib for patients with inoperable liver cancer

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Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis

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Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection

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JOURNAL OF CLINICAL ONCOLOGY (2007)

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Increased regulatory T cells correlate with CD8 T-cell impairment and poor survival in hepatocellular carcinoma patients

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GASTROENTEROLOGY (2007)

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Cross-presentation of antigens from apoptotic tumor cells by liver sinusoidal endothelial cells leads to tumor-specific CD8+ T cell tolerance

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Smad3 reduces susceptibility to hepatocarcinoma by sensitizing hepatocytes to apoptosis through downregulation of Bcl-2

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GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase

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Marginating pulmonary-NK activity and resistance to experimental tumor metastasis:: suppression by surgery and the prophylactic use of a β-adrenergic antagonist and a prostaglandin synthesis inhibitor

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Transforming growth factor-beta 1 marker of small hepatocellular as a useful serologic carcinoma

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Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T cells results in antigen-specific T-cell tolerance

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NATURE MEDICINE (2000)

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