Implementation of routine first-trimester combined screening for preeclampsia based on the Gaussian algorithm: A clinical effectiveness study

Article Obstetrics & Gynecology

Diagnostic accuracy of the Gaussian first-trimester combined screening for pre-eclampsia to predict small-for-gestational-age neonates

Manel Mendoza et al.

Summary: This study showed that early prediction of both pre-eclampsia and SGA is feasible using a Gaussian algorithm. The algorithm identified a significant percentage of early and preterm SGA cases, providing a simplified approach for clinical practice.

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS (2022)

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Article Acoustics

Diagnostic accuracy of first-trimester combined screening for early-onset and preterm pre-eclampsia at 8-10 compared with 11-13 weeks' gestation

M. Mendoza et al.

Summary: This study compared the prediction of early-onset and preterm PE when serum biomarkers were assessed before vs after 11 weeks of gestation, finding similar predictive abilities in both scenarios. This suggests that a two-step approach for PE risk assessment can be used, allowing for immediate risk calculation at the time of the first-trimester scan.

ULTRASOUND IN OBSTETRICS & GYNECOLOGY (2021)

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Article Obstetrics & Gynecology

Implementation of routine first trimester combined screening for pre-eclampsia: a clinical effectiveness study

G. P. Guy et al.

Summary: The study evaluates the clinical effectiveness of implementing a first-trimester combined pre-eclampsia screening program in a public healthcare setting. The results show a significant reduction in screen-positive rate, increased aspirin use, and effective identification of preterm pre-eclampsia.

BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY (2021)

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Article Obstetrics & Gynecology

Cut-off values for Gaussian first-trimester screening for early-onset preeclampsia with maternal history, biochemical markers and uterine artery Doppler

Manel Mendoza et al.

Summary: The study aimed to provide cut-off values for the Gaussian model for first-trimester screening of preeclampsia in clinical practice. It conducted a prospective cohort study of 2641 women with singleton pregnancies to determine cut-off values and detection rates for various combinations of markers.

JOURNAL OF GYNECOLOGY OBSTETRICS AND HUMAN REPRODUCTION (2021)

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Article Obstetrics & Gynecology