期刊
INTERNAL MEDICINE JOURNAL
卷 52, 期 6, 页码 1079-1082出版社
WILEY
DOI: 10.1111/imj.15810
关键词
azithromycin; community-acquired pneumonia; antimicrobial stewardship; prolonged QT interval; arrhythmia; therapeutic guideline
This study showed that a majority of patients with severe community-acquired pneumonia were prescribed azithromycin without undergoing electrocardiograms to assess the QTc interval and without meeting the criteria for severe community-acquired pneumonia. This inappropriate use of azithromycin poses various risks and issues.
Azithromycin is prescribed for atypical antimicrobial cover in severe community-acquired pneumonia. Inappropriate azithromycin administration incurs unnecessary financial costs, exacerbates antimicrobial resistance and risks QTc interval prolongation leading to cardiac arrhythmias. The present study demonstrated that a majority of patients were prescribed azithromycin without having electrocardiograms to assess the QTc interval and without meeting criteria for severe community-acquired pneumonia based on CURB-65 score.
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