4.6 Article

Targeting glycolysis in Th2 cells by pterostilbene attenuates clinical severities in an asthmatic mouse model and IL-4 production in peripheral blood from asthmatic patients

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Inflammatory activation of endothelial cells increases glycolysis and oxygen consumption despite inhibiting cell proliferation

Jonas Aakre Wik et al.

Summary: The study shows that inflammatory activation of human umbilical vein endothelial cells by interleukin-1 beta promotes a shift towards a more metabolically active phenotype, driven by shunting of glucose-derived pyruvate into mitochondria. The metabolic response to IL-1 beta varies significantly among donors, highlighting the importance of considering donor-specific responses when targeting dysregulated endothelial cell metabolism.

FEBS OPEN BIO (2021)

Article Biochemistry & Molecular Biology

The in vitro and in vivo depigmenting activity of pterostilbene through induction of autophagy in melanocytes and inhibition of UVA-irradiated α-MSH in keratinocytes via Nrf2-mediated antioxidant pathways

You-Cheng Hseu et al.

Summary: Research has shown that Pterostilbene has anti-melanogenic effects by inhibiting melanin production through autophagy induction. Experimental results indicate that Pt can suppress melanin synthesis by activating the Nrf2 antioxidant pathway and downregulating genes related to the CREB-MITF pathway, such as TRP-1/-2 and tyrosinase.

REDOX BIOLOGY (2021)

Review Pediatrics

Epidemiology of Asthma in Children and Adults

Shyamaii C. Dharmage et al.

FRONTIERS IN PEDIATRICS (2019)

Review Immunology

The Metabolic Requirements of Th2 Cell Differentiation

Julian M. Stark et al.

FRONTIERS IN IMMUNOLOGY (2019)

Review Biochemistry & Molecular Biology

Role of mTOR in Glucose and Lipid Metabolism

Zhuo Mao et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Review Immunology

Metabolic Adaptations of CD4+ T Cells in inflammatory Disease

Cristina Dumitru et al.

FRONTIERS IN IMMUNOLOGY (2018)

Editorial Material Critical Care Medicine

Severe asthma: looking beyond the amount of medication

Andrew Bush et al.

LANCET RESPIRATORY MEDICINE (2017)

Review Allergy

Asthma Exacerbations: Pathogenesis, Prevention, and Treatment

Jamee R. Castillo et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2017)

Review Allergy

Gut microbiota and allergy/asthma: From pathogenesis to new therapeutic strategies

Y. B. Kang et al.

ALLERGOLOGIA ET IMMUNOPATHOLOGIA (2017)

Article Biochemistry & Molecular Biology

Therapeutic Effect of Histone Deacetylase Inhibitor, Sodium Butyrate, on Allergic Rhinitis In Vivo

Jie Wang et al.

DNA AND CELL BIOLOGY (2016)

Review Allergy

Severe Asthma in Children: Lessons Learned and Future Directions

Anne M. Fitzpatrick

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2016)

Article Multidisciplinary Sciences

Cell surface Glut1 levels distinguish human CD4 and CD8 T lymphocyte subsets with distinct effector functions

Gaspard Cretenet et al.

SCIENTIFIC REPORTS (2016)

Review Biochemistry & Molecular Biology

Mast cell production and response to IL-4 and IL-13

Jamie J. A. McLeod et al.

CYTOKINE (2015)

Article Otorhinolaryngology

Characteristics of traditional Chinese medicine use for children with allergic rhinitis: A nationwide population-based study

Hung-Rong Yen et al.

INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY (2015)

Article Allergy

International consensus on allergy immunotherapy

Marek Jutel et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2015)

Editorial Material Respiratory System

Asthma deaths: what now?

Mark L. Levy et al.

THORAX (2015)

Article Otorhinolaryngology

Dose-response relationship of specific allergen exposure-induced immunological tolerance: a mouse model

Yueh-Chiao Yeh et al.

INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY (2015)

Article Biotechnology & Applied Microbiology

Sesame Oil Attenuates Ovalbumin-Induced Pulmonary Edema and Bronchial Neutrophilic Inflammation in Mice

Dur-Zong Hsu et al.

BIOMED RESEARCH INTERNATIONAL (2013)

Editorial Material Medicine, General & Internal

Call for withdrawal of LABA single-therapy inhaler in asthma

Richard Beasley et al.

LANCET (2010)

Article Agriculture, Multidisciplinary

Pterostilbene suppressed lipopolysaccharide-induced up-expression of MOS and COX-2 in murine macrophages

Min-Hsiung Pan et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2008)