4.7 Article

Health Related Quality of Life after ECT for depression: A study exploring the role of different electrode-placements and pulse-widths

期刊

JOURNAL OF AFFECTIVE DISORDERS
卷 206, 期 -, 页码 268-272

出版社

ELSEVIER SCIENCE BV
DOI: 10.1016/j.jad.2016.08.002

关键词

Electroconvulsive Therapy (ECT); Health-Related-Quality of Life (HRQOL); Pulse-width; Electrode placement

资金

  1. Mental Health Commission of New South Wales (MHC NSW)

向作者/读者索取更多资源

Introduction: Prior research has shown large improvements in HRQOL after a course of ECT for depression. However, the effect of different types of ECT on HRQOL outcomes has not been explored. This is important due to the considerable range of ECT treatment modalities that currently exist in clinical practice. Methods: HRQOL data from 355 depressed patients in three Australian clinical hospitals, who received ECT given with a range of treatment modalities (combinations of pulse-width and electrode-placement), were analysed. HRQOL was measured at baseline and after ECT, using the Quality of Life Enjoyment and Satisfaction Questionnaire-Short Form (Q-LES-Q-SF). The association between type of ECT and HRQOL after ECT was examined by regression analysis, controlling for variables that may affect HRQOL outcomes. Results: There was a significant increase in HRQOL scores after ECT (p < 0.0001; t= -23.4). The magnitude of change was large (54% increase, Cohen's d=1.43). Multiple regression analysis yielded a significant model (P < 0.001, R-2=0.18). Baseline HRQOL score (t=4.83; p < 0.0001), age (t=2.75, p < 0.01) and type of ECT received [Right Unilateral brief vs Bitemporal Ultrabrief (t= -2.99; p < 0.01) and Right Unilateral brief vs Bifrontal Ultrabrief (t= -2.70; p < 0.01)I were significant predictors of HRQOL after the ECT course. Limitations: Data was collected naturalistically from clinical services, thus Ea modality was not randomly assigned. Site could have confounded results. Conclusions: An acute course of ECT for depression produced statistically and clinically significant improvements in HRQOL. ECT treatment modality can substantially impact HRQOL outcomes, with the possibility of bilateral ultrabrief forms of ECT being less beneficial. (C) 2016 Elsevier B.V. All rights reserved.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.7
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据