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Resveratrol protects diabetic kidney by attenuating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via Nrf2-Keap1 signaling
P. Palsamy et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2011)
Regular physical exercise training assists in preventing type 2 diabetes development: focus on its antioxidant and anti-inflammatory properties
Edite Teixeira-Lemos et al.
CARDIOVASCULAR DIABETOLOGY (2011)
Dietary Restriction Ameliorates Diabetic Nephropathy through Anti-Inflammatory Effects and Regulation of the Autophagy via Restoration of Sirt1 in Diabetic Wistar Fatty (fa/fa) Rats: A Model of Type 2 Diabetes
Munehiro Kitada et al.
EXPERIMENTAL DIABETES RESEARCH (2011)
Diabetic Nephropathy Amelioration by a Low-Dose Sitagliptin in an Animal Model of Type 2 Diabetes (Zucker Diabetic Fatty Rat)
Cristina Mega et al.
EXPERIMENTAL DIABETES RESEARCH (2011)
In vitro suppression of quercetin on hypertrophy and extracellular matrix accumulation in rat glomerular mesangial cells cultured by high glucose
Dao-quan Tang et al.
FITOTERAPIA (2011)
Oxidative stress and the etiology of insulin resistance and type 2 diabetes
Erik J. Henriksen et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
Oxidative stress, insulin signaling, and diabetes
Justin L. Rains et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
Silver nanoparticles induce oxidative cell damage in human liver cells through inhibition of reduced glutathione and induction of mitochondria-involved apoptosis
Mei Jing Piao et al.
TOXICOLOGY LETTERS (2011)
Glucolipotoxicity in Pancreatic β-Cells
Ji-Won Kim et al.
DIABETES & METABOLISM JOURNAL (2011)
Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2
Zoltan Ungvari et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2010)
Prevention of diabetic nephropathy in Ins2+/-AkitaJ mice by the mitochondria-targeted therapy MitoQ
Balu K. Chacko et al.
BIOCHEMICAL JOURNAL (2010)
Resveratrol, a dietary polyphenolic phytoalexin, is a functional scavenger of peroxynitrite
Joseph H. Holthoff et al.
BIOCHEMICAL PHARMACOLOGY (2010)
Calorie Restriction Reduces Oxidative Stress by SIRT3-Mediated SOD2 Activation
Xiaolei Qiu et al.
CELL METABOLISM (2010)
Activation of Protein Kinase C Isoforms and Its Impact on Diabetic Complications
Pedro Geraldes et al.
CIRCULATION RESEARCH (2010)
Caloric restriction improves endothelial dysfunction during vascular aging Effects on nitric oxide synthase isoforms and oxidative stress in rat aorta
Michela Zanetti et al.
EXPERIMENTAL GERONTOLOGY (2010)
After cellular internalization, quercetin causes Nrf2 nuclear translocation, increases glutathione levels, and prevents neuronal death against an oxidative insult
Florencia Arredondo et al.
FREE RADICAL BIOLOGY AND MEDICINE (2010)
Oxidatively generated base damage to cellular DNA
Jean Cadet et al.
FREE RADICAL BIOLOGY AND MEDICINE (2010)
Antioxidant properties of resveratrol: A structure-activity insight
Ilhami Gulcin
INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES (2010)
Targeting beta-Cell Function Early in the Course of Therapy for Type 2 Diabetes Mellitus
Jack L. Leahy et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2010)
Dietary Interventions to Extend Life Span and Health Span Based on Calorie Restriction
Robin K. Minor et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2010)
Green tea polyphenol epigallocatechi3-gallate: Inflammation and arthritis
Rashmi Singh et al.
LIFE SCIENCES (2010)
Epigallocatechin-3-gallate activates Nrf2/HO-1 signaling pathway in cisplatin-induced nephrotoxicity in rats
Kazim Sahin et al.
LIFE SCIENCES (2010)
Anti-inflammatory effect of exercise training in subjects with type 2 diabetes and the metabolic syndrome is dependent on exercise modalities and independent of weight toss
S. Balducci et al.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES (2010)
Multifaceted approach to resveratrol bioactivity Focus on antioxidant action, cell signaling and safety
Peter Kovacic et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2010)
Sirtuin 3, a New Target of PGC-1α, Plays an Important Role in the Suppression of ROS and Mitochondrial Biogenesis
Xingxing Kong et al.
PLOS ONE (2010)
Vitamins C and E treatment combined with exercise modulates oxidative stress markers in blood of patients with fibromyalgia: A controlled clinical pilot study
Mustafa Naziroglu et al.
STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS (2010)
ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function
Jingbo Pi et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2010)
Critical role of Nox4-based NADPH oxidase in glucose-induced oxidative stress in the kidney: implications in type 2 diabetic nephropathy
M. Sedeek et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2010)
Modulation of Titin-Based Stiffness by Disulfide Bonding in the Cardiac Titin N2-B Unique Sequence
Anika Gruetzner et al.
BIOPHYSICAL JOURNAL (2009)
Oxidative stress and human diseases: Origin, link, measurement, mechanisms, and biomarkers
Daniela Giustarini et al.
CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES (2009)
The Role of the Gut Microbiota in Energy Metabolism and Metabolic Disease
Patrice D. Cani et al.
CURRENT PHARMACEUTICAL DESIGN (2009)
Effects and clinical potential of very-low-calorie diets (VLCDs) in type 2 diabetes
Scott Baker et al.
DIABETES RESEARCH AND CLINICAL PRACTICE (2009)
Oxidant stress-induced loss of IRS-1 and IRS-2 proteins in rat skeletal muscle: Role of p38 MAPK
Tara L. Archuleta et al.
FREE RADICAL BIOLOGY AND MEDICINE (2009)
Oxidative stress and metabolic syndrome
Christian K. Roberts et al.
LIFE SCIENCES (2009)
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
Carles Canto et al.
NATURE (2009)
Subcellular localization of Nox4 and regulation in diabetes
Karen Block et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Epigallocatechin-3-gallate augments antioxidant activities and inhibits inflammation during bleomycin-induced experimental pulmonary fibrosis through Nrf2-Keap1 signaling
Narayanan Sriram et al.
PULMONARY PHARMACOLOGY & THERAPEUTICS (2009)
Lipoperoxidation and antioxidant capacity in patients with poorly controlled type 2 diabetes
M. Lodovici et al.
TOXICOLOGY AND INDUSTRIAL HEALTH (2009)
Plasma vitamin C level, fruit and vegetable consumption, and the risk of new-onset type 2 diabetes mellitus - The European Prospective Investigation of Cancer-Norfolk prospective study
Anne-Helen Harding et al.
ARCHIVES OF INTERNAL MEDICINE (2008)
Catalase Deficiency and Type 2 Diabetes
L. Goth
DIABETES CARE (2008)
Effect of caloric restriction with and without exercise training on oxidative stress and endothelial function in obese subjects with type 2 diabetes
T. P. Wycherley et al.
DIABETES OBESITY & METABOLISM (2008)
Modulation of Nrf2-mediated antioxidant and detoxifying enzyme induction by the green tea polyphenol EGCG
Hye-Kyung Na et al.
FOOD AND CHEMICAL TOXICOLOGY (2008)
Angiotensin II:: A hormone involved in and contributing to pro-hypertrophic cardiac networks and target of anti-hypertrophic cross-talks
K.-D. Schlueter et al.
PHARMACOLOGY & THERAPEUTICS (2008)
Inflammation in the vascular bed: Importance of vitamin C
Rene Aguirre et al.
PHARMACOLOGY & THERAPEUTICS (2008)
Curcumin downregulates the inflammatory cytokines CXCL1 and-2 in breast cancer cells via NF kappa B
Beatrice E. Bachmeier et al.
CARCINOGENESIS (2008)
Mitochondrial medicine: Pharmacological targeting of mitochondria in disease
J. S. Armstrong
BRITISH JOURNAL OF PHARMACOLOGY (2007)
Blockade of oxidative stress by vitamin C ameliorates albuminuria and renal sclerosis in experimental diabetic rats
Eun Young Lee et al.
YONSEI MEDICAL JOURNAL (2007)
Protein glutathionylation and oxidative stress
Toshimitsu Niwa
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2007)
Supplementation with vitamins C and E improves arterial stiffness and endothelial function in essential hypertensive patients
Yvonne Plantinga et al.
AMERICAN JOURNAL OF HYPERTENSION (2007)
Effects of resveratrol on nerve functions, oxidative stress and DNA fragmentation in experimental diabetic neuropathy
Ashutosh Kumar et al.
LIFE SCIENCES (2007)
Differential effects of oral hypoglycemic agents on glucose control and cardiovascular risk
Gabriel I. Uwaifo et al.
AMERICAN JOURNAL OF CARDIOLOGY (2007)
Inhibition of DPP-4: a new therapeutic approach for the treatment of type 2 diabetes
Richard E. Pratley et al.
CURRENT MEDICAL RESEARCH AND OPINION (2007)
AGE, RAGE, and ROS in diabetic nephropathy
Adeline L. Y. Ton et al.
SEMINARS IN NEPHROLOGY (2007)
Free radicals and antioxidants in normal physiological functions and human disease
Marian Valko et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2007)
Therapeutic potential of (-)-epigallocatechin 3-O-gallate on renal damage in diabetic nephropathy model rats
Noriko Yamabe et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
Advanced glycation end products - Sparking the development of diabetic vascular injury
Alison Goldin et al.
CIRCULATION (2006)
Molecular mechanisms of insulin resistance:: Serine phosphorylation of insulin receptor substrate-1 and increased expression of p85α -: The two sides of a coin
Boris Draznin
DIABETES (2006)
Content of redox-active compounds (ie, antioxidants) in foods consumed in the United States
Bente L. Halvorsen et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2006)
TAGE (toxic AGEs) theory in diabetic complications
Takashi Sato et al.
CURRENT MOLECULAR MEDICINE (2006)
Curcumin activates defensive genes and protects neurons against oxidative stress
Giovanni Scapagnini et al.
ANTIOXIDANTS & REDOX SIGNALING (2006)
Critical nodes in signalling pathways: insights into insulin action
CM Taniguchi et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)
Neuroprotective and blood-retinal barrier-preserving effects of cannabidiol in experimental diabetes
AB El-Remessy et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
Hexosamines, insulin resistance, and the complications of diabetes: current status
MG Buse
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2006)
Upregulation of endogenous antioxidants and phase 2 enzymes by the red wine polyphenol, resveratrol in cultured aortic smooth muscle cells leads to cytoprotection against oxidative and electrophilic stress
YB Li et al.
PHARMACOLOGICAL RESEARCH (2006)
Proposed mechanisms for the induction of insulin resistance by oxidative stress
A Bloch-Damti et al.
ANTIOXIDANTS & REDOX SIGNALING (2005)
Curcumin and turmeric delay streptozotocin-induced diabetic cataract in rats
P Suryanarayana et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)
Role of aldose reductase and oxidative damage in diabetes and the consequent potential for therapeutic options
SK Srivastava et al.
ENDOCRINE REVIEWS (2005)
PKC-δ-dependent activation of oxidative stress in adipocytes of obese and insulin-resistant mice:: role for NADPH oxidase
I Talior et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2005)
Protective role of tea catechins against oxidation-induced damage of type 2 diabetic erythrocytes
SI Rizvi et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2005)
Epidemiological evidence for the role of physical activity in reducing risk of type 2 diabetes and cardiovascular disease
SS Bassuk et al.
JOURNAL OF APPLIED PHYSIOLOGY (2005)
Quercetin, an anti-oxidant bioflavonoid, attenuates diabetic nephropathy in rats
M Anjaneyulu et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2004)
Drug therapy: Thiazolidinediones
H Yki-Jarvinen
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Antioxidant vitamin supplements and cardiovascular disease
PM Kris-Etherton et al.
CIRCULATION (2004)
Activation of the hexosamine pathway causes oxidative stress and abnormal embryo gene expression:: Involvement in diabetic teratogenesis
M Horal et al.
BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY (2004)
Oxidative stress induces nucleo-cytoplasmic translocation of pancreatic transcription factor PDX-1 through activation of c-Jun NH2-terminal kinase
D Kawamori et al.
DIABETES (2003)
Oxidative stress is associated with adiposity and insulin resistance in men
H Urakawa et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2003)
The role of advanced glycation in the pathogenesis of diabetic retinopathy
AW Stitt
EXPERIMENTAL AND MOLECULAR PATHOLOGY (2003)
The metabolic syndrome:: Peroxisome proliferator-activated receptor γ and its therapeutic modulation
M Gurnell et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2003)
The role of oxidative stress in diabetic vascular and neural disease
MA Yorek
FREE RADICAL RESEARCH (2003)
Curcurnin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element
E Balogun et al.
BIOCHEMICAL JOURNAL (2003)
Glucose toxicity in β-cells:: Type 2 diabetes, good radicals gone bad, and the glutathione connection
RP Robertson et al.
DIABETES (2003)
PTP1B inhibitors as potential therapeutics in the treatment of Type 2 diabetes and obesity
ZY Zhang et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2003)
Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction?
JL Evans et al.
DIABETES (2003)
Metformin - New understandings, new uses
RS Hundal et al.
DRUGS (2003)
Involvement of c-Jun N-terminal kinase in oxidative stress-mediated suppression of insulin gene expression
H Kaneto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Protection of flavonoids against lipid peroxidation: The structure activity relationship revisited
CGM Heijnen et al.
FREE RADICAL RESEARCH (2002)
Dietary fat and meat intake in relation to risk of type 2 diabetes in men
RM van Dam et al.
DIABETES CARE (2002)
Efficacy of turmeric on blood sugar and polyol pathway in diabetic albino rats
N Arun et al.
PLANT FOODS FOR HUMAN NUTRITION (2002)
Biochemistry and molecular cell biology of diabetic complications
M Brownlee
NATURE (2001)
Activation of the hexosamine pathway leads to deterioration of pancreatic β-cell function through the induction of oxidative stress
H Kaneto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The role of oxidative stress in the onset and progression of diabetes and its complications:: a summary of a Congress Series sponsored by UNESCO-MCBN, the American Diabetes Association and the German Diabetes Society
P Rösen et al.
DIABETES-METABOLISM RESEARCH AND REVIEWS (2001)
Pharmacologic therapy for type 2 diabetes mellitus
RA DeFronzo
ANNALS OF INTERNAL MEDICINE (2000)
Protein kinase C signaling and oxidative stress
R Gopalakrishna et al.
FREE RADICAL BIOLOGY AND MEDICINE (2000)
Dual action of the active oxygen species during plant stress responses
J Dat et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2000)
What is oxidative stress?
DJ Betteridge
METABOLISM-CLINICAL AND EXPERIMENTAL (2000)
A prospective study of whole-grain intake and risk of type 2 diabetes mellitus in US women
SM Liu et al.
AMERICAN JOURNAL OF PUBLIC HEALTH (2000)
Role of the hexosamine biosynthetic pathway in diabetic nephropathy
ED Schleicher et al.
KIDNEY INTERNATIONAL (2000)