4.0 Article

Therapy of Sialorrhea with Botulinum Toxin - An Update

期刊

FORTSCHRITTE DER NEUROLOGIE PSYCHIATRIE
卷 90, 期 5, 页码 222-232

出版社

GEORG THIEME VERLAG KG
DOI: 10.1055/a-1802-3867

关键词

sialorrhea; dysphagia; anticholinergics; botulinum toxin

向作者/读者索取更多资源

The most important salivary glands are the paired parotid and submandibular glands. Increased saliva production can impair quality of life, and treatment options include conservative measures, anticholinergic medication, and injection therapy.
The most important salivary glands are the paired parotid and submandibular glands. Adults produce 1 to 1.5 liters of saliva which are then regularly swallowed. When the act of swallowing is disturbed, salivation occurs. More rarely, the cause can be found in increased saliva production, for example, when caused through medication. Sialorrhea impairs the quality of life substantially and is frequently often socially stigmatizing. Therapy includes conservative measures such as functional dysphagia therapy, oral ortransdermal application of anticholinergics, as well as, in selected cases, radiation and surgical measures. Over the last 20 years, local injection of botulinum toxin has been successfully applied in the treatment of this condition. With approval of incobotulinumtoxinA toxin for children and adults, this procedure will become the therapy of choice for chronic sialorrhea. The results of the phase Ill registration trials have demonstrated high efficacy and good safety of the injection treatment in both children and adults.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.0
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据