期刊
FOOD CHEMISTRY
卷 373, 期 -, 页码 -出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.foodchem.2021.131482
关键词
Premna microphylla Turcz; UPLC-LTQ-Orbitrap-MS; Qualitative analysis; Antioxidant activity
资金
- National Natural Science Foundation of China [8217021815]
- Anhui Natural Science Foundation [2008085J39, 2108085MH314]
- Natural Science Foundation of Anhui Educational Committee [KJ2020A0728]
- State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Guangxi Normal University) [CMEMR2021-B03]
- Excellent top-notch Talents Training program of Anhui Universities [gxgwfx2021038]
- Key Disciplines of Pharmacy [2019xjzdxk2]
- Back-up Candidates for Academic and Technical Leaders of Suzhou University [2018XJHB06]
- Suzhou Engineering Research Center of Natural Medicine and Functional Food [SZ2017ZX06]
The study identified 18 compounds in the stem of Premna microphylla Turcz., with 6 compounds being identified for the first time within this genus and plant. These compounds highlight the strong therapeutic potential of Premna microphylla Turcz. stem extract against oxidation-related diseases.
Premna microphylla Turcz. is a commonly used traditional Chinese medicine to treat dysentery and appendicitis. Present study is focused to explore antioxidants and other compounds in the Premna microphylla Turcz. stem. Assessment of chemical composition was done with high sensitivity UPLC-LTQ-Orbitrap-MS and for Separation Thermo Hypersil Gold (100 mm x 2.1 mm, 1.9 mu m) was used while electrospray ionization (ESI) was used for the mass spectrometry. 18 compounds were identified including Vitexin (1), Schaftoside (2), Vicenin-2 (3), Apigenin6, 8-di-C-arabinoside (4), Apigenin-7-O-beta-D-glucoside (5), Carnosic acid (6), Apigenin-8-C-beta-D-xylopyranoside (7), Prostratin (8), Aurantio-obtusin-beta-D-glucoside (9), Royleanone (10), 5-hydroxy-7,3',4'-Trimethoxy flavonols (11), 6-Hydroxy-5,6-dehydrosugiol (12), 14-deoxycoleon (13), Arucadiol (14), Obtusinone-B (15), Trehalose (16), Citric acid (17) and Betaine (18). Among these, 6 compounds including (6), (8), (9), (16), (17) and (18) were identified first time within this genus and plant. Study highlights the importance of Premna microphylla Turcz. stem extract for strong therapeutic potential against oxidation-related diseases.
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