4.5 Review

Evaluating pharmacokinetic drug-drug interactions of direct oral anticoagulants in patients with renal dysfunction

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Pharmacology & Pharmacy

Quantitative Benefit-Risk Assessment of P-gp-Mediated Drug-Drug Interactions of Dabigatran Coadministered With Pharmacokinetic Enhancers in Patients With Renal Impairment

Karthik Lingineni et al.

Summary: Drug-drug interactions between dabigatran and ritonavir/cobicistat may increase the risk of bleeding events in people living with HIV, especially those with impaired renal function. Dose adjustments should be considered based on renal function status to mitigate potential adverse effects.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2021)

Article Hematology

A retrospective study of indications and consequences of monitoring direct oral anticoagulant plasma concentrations on patient care in a university hospital: The Retro-AOD study

Thibaud Cavaillez et al.

Summary: The study aimed to describe the indications and consequences of monitoring DOAC plasma levels on patient care, with various clinical situations leading to different responses from physicians. Results showed that patient care was not significantly modified in more than half of the DOAC assays.

THROMBOSIS RESEARCH (2021)

Article Urology & Nephrology

Safety and Efficacy of Vitamin K Antagonists versus Rivaroxaban in Hemodialysis Patients with Atrial Fibrillation: A Multicenter Randomized Controlled Trial

An S. De Vriese et al.

Summary: In hemodialysis patients with atrial fibrillation, the Valkyrie study found that reduced dose of rivaroxaban significantly decreased the composite outcome of fatal and nonfatal cardiovascular events and major bleeding complications compared with VKA.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2021)

Article Chemistry, Multidisciplinary

Investigating Intestinal Transporter Involvement in Rivaroxaban Disposition through Examination of Changes in Absorption

Wen Kou et al.

Summary: In the metabolism of rivaroxaban, the involvement of intestinal efflux transporters has little clinical significance, with drug interactions most likely predicted based on CYP metabolism levels.

PHARMACEUTICAL RESEARCH (2021)

Article Medical Laboratory Technology

Severe Inflammation, Acute Kidney Injury, and Drug-Drug Interaction: Triple Penalty for Prolonged Elimination of Apixaban in Patients With Coronavirus Disease 2019: A Grand Round

Manon Launay et al.

Summary: This article presents a case of apixaban elimination prolonged in a patient with COVID-19 due to various factors, and emphasizes the importance of dialogue between the clinician and a therapeutic drug monitoring consultant for optimal patient care.

THERAPEUTIC DRUG MONITORING (2021)

Article Cardiac & Cardiovascular Systems

Reclassification, Thromboembolic, and Major Bleeding Outcomes Using Different Estimates of Renal Function in Anticoagulated Patients With Atrial Fibrillation Insights From the PREFER-in-AF and PREFER-in-AF Prolongation Registries

Miklos Rohla et al.

Summary: The use of MDRD and CKD-EPI formulas in studying patients taking anticoagulants resulted in up to a quarter of patients being reclassified in terms of dosage, which may have an impact on clinical outcomes.

CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES (2021)

Article Cardiac & Cardiovascular Systems

Oral Anticoagulation for Patients With Atrial Fibrillation on Long-Term Hemodialysis

Toshiki Kuno et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2020)

Article Cardiac & Cardiovascular Systems

The real world use of combined P-glycoprotein and moderate CYP3A4 inhibitors with rivaroxaban or apixaban increases bleeding

Sarah Hanigan et al.

JOURNAL OF THROMBOSIS AND THROMBOLYSIS (2020)

Article Medicine, General & Internal

Possible Interaction between Dabigatran and Ranolazine in Patients with Renal Failure

Gintautas Gumbrevicius et al.

MEDICINA-LITHUANIA (2020)

Article Pharmacology & Pharmacy

Supratheraputic rivaroxaban levels: A persistent drug-drug interaction after discontinuation of amiodarone

Kenneth Skov et al.

BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2020)

Article Chemistry, Multidisciplinary

Intestinal Efflux Transporters P-gp and BCRP Are Not Clinically Relevant in Apixaban Disposition

Jasleen K. Sodhi et al.

PHARMACEUTICAL RESEARCH (2020)

Review Pharmacology & Pharmacy

Apixaban: A Clinical Pharmacokinetic and Pharmacodynamic Review

Wonkyung Byon et al.

CLINICAL PHARMACOKINETICS (2019)

Article Cardiac & Cardiovascular Systems

Frequency and prognostic impact of acute kidney injury in patients with acute pulmonary embolism. Data from the RIETE registry

Martin Murgier et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2019)

Article Pharmacology & Pharmacy

In Vitro Comparison of the Role of P-Glycoprotein and Breast Cancer Resistance Protein on Direct Oral Anticoagulants Disposition

Sophie Hodin et al.

EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS (2018)

Letter Cardiac & Cardiovascular Systems

Rivaroxaban With and Without Amiodarone in Renal Impairment

Eleanor Jing Yi Cheong et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2018)

Article Cardiac & Cardiovascular Systems

A Rare Case of Spontaneous Cardiac Tamponade Induced by Concomitant Use of Rivaroxaban and Amiodarone

Oreoluwa Oladiran et al.

CASE REPORTS IN CARDIOLOGY (2018)

Article Cardiac & Cardiovascular Systems

Predictors of pre-procedural concentrations of direct oral anticoagulants: a prospective multicentre study

Anne Godier et al.

EUROPEAN HEART JOURNAL (2017)

Article Urology & Nephrology

Apixaban Pharmacokinetics at Steady State in Hemodialysis Patients

Thomas A. Mavrakanas et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2017)

Article Pharmacology & Pharmacy

Pharmacokinetics, pharmacodynamics, and safety of apixaban in subjects with end-stage renal disease on hemodialysis

Xiaoli Wang et al.

JOURNAL OF CLINICAL PHARMACOLOGY (2016)

Article Pharmacology & Pharmacy

Effect of renal impairment on the pharmacokinetics, pharmacodynamics, and safety of apixaban

Ming Chang et al.

JOURNAL OF CLINICAL PHARMACOLOGY (2016)

Article Urology & Nephrology

Pharmacokinetics, Pharmacodynamics, and Safety of Single-Dose Rivaroxaban in Chronic Hemodialysis

Clapton Dias et al.

AMERICAN JOURNAL OF NEPHROLOGY (2016)

Review Cardiac & Cardiovascular Systems

Nonvitamin K Anticoagulant Agents in Patients With Advanced Chronic Kidney Disease or on Dialysis With AF

Kevin E. Chan et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2016)

Article Pharmacology & Pharmacy

Effect of ketoconazole and diltiazem on the pharmacokinetics of apixaban, an oral direct factor Xa inhibitor

Charles E. Frost et al.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2015)

Article Cardiac & Cardiovascular Systems

Fatal intracerebral bleeding under rivaroxaban

Claudia Stoellberger et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2015)

Article Pharmacology & Pharmacy

Population pharmacokinetics of edoxaban and its main metabolite in a dedicated renal impairment study

Siv Jonsson et al.

JOURNAL OF CLINICAL PHARMACOLOGY (2015)

Review Pharmacology & Pharmacy

Clinical Pharmacokinetic and Pharmacodynamic Profile of Rivaroxaban

Wolfgang Mueck et al.

CLINICAL PHARMACOKINETICS (2014)

Article Medicine, General & Internal

Gastrointestinal bleeding under dabigatran

C. Stoellberger et al.

JOURNAL OF POSTGRADUATE MEDICINE (2014)

Article Cardiac & Cardiovascular Systems

Amiodarone, Anticoagulation, and Clinical Events in Patients With Atrial Fibrillation Insights From the ARISTOTLE Trial

Greg Flaker et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2014)

Article Cardiac & Cardiovascular Systems

Ischemic Stroke and Intestinal Bleeding Under Dabigatran in Metabolic Myopathy

Josef Finsterer et al.

CARDIOVASCULAR THERAPEUTICS (2013)

Article Medicine, General & Internal

Edoxaban versus Warfarin for the Treatment of Symptomatic Venous Thromboembolism

Harry R. Bueller et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Article Medicine, General & Internal

Edoxaban versus Warfarin in Patients with Atrial Fibrillation

Robert P. Giugliano et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Article Medicine, General & Internal

Oral Apixaban for the Treatment of Acute Venous Thromboembolism

Giancarlo Agnelli et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Article Pharmacology & Pharmacy

Characterization of Efflux Transporters Involved in Distribution and Disposition of Apixaban

Donglu Zhang et al.

DRUG METABOLISM AND DISPOSITION (2013)

Article Medicine, General & Internal

Apixaban versus Warfarin in Patients with Atrial Fibrillation

Christopher B. Granger et al.

NEW ENGLAND JOURNAL OF MEDICINE (2011)

Article Medicine, General & Internal

Rivaroxaban versus Warfarin in Nonvalvular Atrial Fibrillation

Manesh R. Patel et al.

NEW ENGLAND JOURNAL OF MEDICINE (2011)

Article Pharmacology & Pharmacy

Effects of renal impairment on the pharmacokinetics, pharmacodynamics and safety of rivaroxaban, an oral, direct Factor Xa inhibitor

Dagmar Kubitza et al.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2010)

Article Medicine, General & Internal

Oral Rivaroxaban for Symptomatic Venous Thromboembolism.

Rupert Bauersachs et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Article Medicine, General & Internal

Dabigatran versus Warfarin in Patients with Atrial Fibrillation.

Stuart J. Connolly et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)

Article Medicine, General & Internal

Dabigatran versus Warfarin in the Treatment of Acute Venous Thromboembolism.

Sam Schulman et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)