4.7 Article

Reduced dopaminergic neuron degeneration and global transcriptional changes in Parkinson's disease mouse brains engrafted with human neural stems during the early disease stage

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Neurosciences

Modulation of gene expression on a transcriptome-wide level following human neural stem cell transplantation in aged mouse stroke brains

Milton H. Hamblin et al.

Summary: The study demonstrated the therapeutic potential of hNSC transplantation in aged mice post-stroke, showing significant reduction in infarct size and attenuation of proinflammatory factors and matrix metalloproteases induction. RNA sequencing analysis revealed differentially expressed genes and molecular pathways induced by hNSCs, providing insights for developing new therapies for early-stage stroke injury.

EXPERIMENTAL NEUROLOGY (2022)

Review Biochemistry & Molecular Biology

Neural Stem Cells for Early Ischemic Stroke

Milton H. Hamblin et al.

Summary: Neural stem cell transplantation shows promise in treating ischemic stroke by potentially therapeutic actions against neurovascular injury. By secreting factors that stimulate endogenous repair mechanisms, NSCs can promote self-recovery in early-stage ischemic stroke and improve short-term and long-term stroke outcomes.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Multidisciplinary Sciences

Metabolic alterations in Parkinson's disease astrocytes

Tuuli-Maria Sonninen et al.

SCIENTIFIC REPORTS (2020)

Article Multidisciplinary Sciences

Chemical mutagenesis of a GPCR ligand: Detoxifying inflammo-attraction to direct therapeutic stem cell migration

Jean-Pyo Lee et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Review Neurosciences

Dysfunction of Cellular Proteostasis in Parkinson's Disease

Sarka Lehtonen et al.

FRONTIERS IN NEUROSCIENCE (2019)

Article Biochemistry & Molecular Biology

The Encyclopedia of DNA elements (ENCODE): data portal update

Carrie A. Davis et al.

NUCLEIC ACIDS RESEARCH (2018)

Review Clinical Neurology

Mitochondrial Dysfunction in Parkinson's Disease: New Mechanistic Insights and Therapeutic Perspectives

Jin-Sung Park et al.

CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS (2018)

Editorial Material Cell Biology

Brain repair for Parkinson's disease: is the answer in the matrix?

Niamh Moriarty et al.

NEURAL REGENERATION RESEARCH (2018)

Review Cell & Tissue Engineering

Neural stem cell therapy for subacute and chronic ischemic stroke

Austin C. Boese et al.

STEM CELL RESEARCH & THERAPY (2018)

Article Neurosciences

Prevalence of Parkinson's disease across North America

C. Marras et al.

NPJ PARKINSONS DISEASE (2018)

Review Biochemistry & Molecular Biology

Mitochondrial Sirtuins and Molecular Mechanisms of Aging

Robert A. H. van de Ven et al.

TRENDS IN MOLECULAR MEDICINE (2017)

Article Biochemical Research Methods

MultiQC: summarize analysis results for multiple tools and samples in a single report

Philip Ewels et al.

BIOINFORMATICS (2016)

Article Clinical Neurology

Epidemiology of Parkinson's disease

A. Elbaz et al.

REVUE NEUROLOGIQUE (2016)

Review Neurosciences

Decoding Parkinson's Disease Pathogenesis: The Role of Deregulated mRNA Translation

Ian Martin

JOURNAL OF PARKINSONS DISEASE (2016)

Article Medicine, General & Internal

Parkinson's disease

Lorraine V. Kalia et al.

LANCET (2015)

Article Cell Biology

Sirtuins, metabolism, and DNA repair

Jee-Eun Choi et al.

CURRENT OPINION IN GENETICS & DEVELOPMENT (2014)

Article Cell Biology

Long-Term Health of Dopaminergic Neuron Transplants in Parkinson's Disease Patients

Penelope J. Hallett et al.

CELL REPORTS (2014)

Article Clinical Neurology

Long-term Clinical Outcome of Fetal Cell Transplantation for Parkinson Disease Two Case Reports

Zinovia Kefalopoulou et al.

JAMA NEUROLOGY (2014)

Article Biotechnology & Applied Microbiology

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Michael I. Love et al.

GENOME BIOLOGY (2014)

Article Biochemical Research Methods

STAR: ultrafast universal RNA-seq aligner

Alexander Dobin et al.

BIOINFORMATICS (2013)

Article Biochemistry & Molecular Biology

Induction of KLF4 Contributes to the Neurotoxicity of MPP + in M17 Cells: A New Implication in Parkinson's Disease

Jinbo Chen et al.

JOURNAL OF MOLECULAR NEUROSCIENCE (2013)

Review Pharmacology & Pharmacy

The Pharmacology of L-DOPA-Induced Dyskinesia in Parkinson's Disease

Philippe Huot et al.

PHARMACOLOGICAL REVIEWS (2013)

Article Biochemical Research Methods

NIH Image to ImageJ: 25 years of image analysis

Caroline A. Schneider et al.

NATURE METHODS (2012)

Article Biochemical Research Methods

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

Bo Li et al.

BMC BIOINFORMATICS (2011)

Review Behavioral Sciences

Behavioral phenotyping of mouse models of Parkinson's disease

Tonya N. Taylor et al.

BEHAVIOURAL BRAIN RESEARCH (2010)

Article Multidisciplinary Sciences

Communication via gap junctions underlies early functional and beneficial interactions between grafted neural stem cells and the host

Johan Jaderstad et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Clinical Neurology

A clinico-pathological study of subtypes in Parkinson's disease

M. Selikhova et al.

Article Multidisciplinary Sciences

Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells

D. Eugene Redmond et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Biochemistry & Molecular Biology

Stem cells act through multiple mechanisms to benefit mice with neurodegenerative metabolic disease

Jean-Pyo Lee et al.

NATURE MEDICINE (2007)

Article Biophysics

MPTP as a mitochondrial neurotoxic model of Parkinson's disease

S Przedborski et al.

JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2004)

Article Multidisciplinary Sciences

Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1α/CXC chemokine receptor 4 pathway

J Imitola et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Review Cell Biology

Stages in the development of Parkinson's disease-related pathology

H Braak et al.

CELL AND TISSUE RESEARCH (2004)

Article Clinical Neurology

Dopamine agonists, receptor selectivity and dyskinesia induction in Parkinson's disease

P Jenner

CURRENT OPINION IN NEUROLOGY (2003)

Article Medicine, General & Internal

Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced Parkinson's disease

P Krack et al.

NEW ENGLAND JOURNAL OF MEDICINE (2003)

Article Biochemistry & Molecular Biology

Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle

SC Dryden et al.

MOLECULAR AND CELLULAR BIOLOGY (2003)

Review Neurosciences

Pathogenesis of Parkinson's disease:: Dopamine, vesicles and α-synuclein

J Lotharius et al.

NATURE REVIEWS NEUROSCIENCE (2002)

Article Biotechnology & Applied Microbiology

Neural stem cells display an inherent mechanism for rescuing dysfunctional neurons

J Ourednik et al.

NATURE BIOTECHNOLOGY (2002)

Article Medicine, General & Internal

Transplantation of embryonic dopamine neurons for severe Parkinson's disease.

CR Freed et al.

NEW ENGLAND JOURNAL OF MEDICINE (2001)