期刊
ADVANCED DRUG DELIVERY REVIEWS
卷 89, 期 -, 页码 21-41出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.addr.2015.01.005
关键词
Raman imaging; Drug delivery; Chemometrics; Multivariate methods; Pre-processing; Solid dispersions; Drug dissolution; Polymeric microparticles
This review article includes an introduction to the principals of Raman spectroscopy, an outline of the experimental systems used for Raman imaging and the associated important considerations and limitations of this method. Common spectral analysis methods are briefly described and examples of interesting published studies which utilised Raman imaging of pharmaceutical and biomedical devices are discussed, along with summary tables of the literature at this point in time. (C) 2015 Elsevier B.V. All rights reserved.
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