4.7 Review

Raman imaging of drug delivery systems

期刊

ADVANCED DRUG DELIVERY REVIEWS
卷 89, 期 -, 页码 21-41

出版社

ELSEVIER SCIENCE BV
DOI: 10.1016/j.addr.2015.01.005

关键词

Raman imaging; Drug delivery; Chemometrics; Multivariate methods; Pre-processing; Solid dispersions; Drug dissolution; Polymeric microparticles

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This review article includes an introduction to the principals of Raman spectroscopy, an outline of the experimental systems used for Raman imaging and the associated important considerations and limitations of this method. Common spectral analysis methods are briefly described and examples of interesting published studies which utilised Raman imaging of pharmaceutical and biomedical devices are discussed, along with summary tables of the literature at this point in time. (C) 2015 Elsevier B.V. All rights reserved.

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