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Role of fruits in aging and age-related disorders

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EXPERIMENTAL GERONTOLOGY
卷 162, 期 -, 页码 -

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PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.exger.2022.111763

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Telomere; Reactive oxygen spices; Sirt 1; AMPK; Aging; Oxidative stress

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Aging is a process that leads to decline in maximum function and death of an organism. Diet therapy, particularly consuming fruits, seems to be the most appropriate approach to combat aging, as fruits contain various compounds that have anti-aging properties.
Aging is a collection of changes that contribute to decline in maximum function and ultimately death of an organism. This process is controlled and initiated by several mechanisms including telomere shortening, oxidative stress, AMP-activated protein kinase and sirt-1. Several therapies have been reported to relieve the process of aging. Among these, diet therapy seems to be the most appropriate approach. Fruits are an important part of regular diet. They contain several compounds which have potential to handle the problem of aging and its related disorders. The present paper provides a comprehensive review on different factors present in various fruits related to the process of aging together with their antiaging mechanisms.

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