4.6 Article

T2-high asthma phenotypes across lifespan

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Allergy

The Prevalence of Subtypes of Type 2 Inflammation in an Unselected Population of Patients with Severe Asthma

Laurits Frossing et al.

Summary: This study examined the expression levels of T2 inflammatory markers in patients with severe asthma and their relationship with clinical characteristics and comorbidities. The majority of patients exhibited at least one T2 inflammatory trait, and the coexpression of T2 biomarkers showed high heterogeneity with distinct clinical characteristics.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2021)

Article Medicine, Research & Experimental

Preventing asthma in high risk kids (PARK) with omalizumab: Design, rationale, methods, lessons learned and adaptation

Wanda Phipatanakul et al.

Summary: Asthma in children is largely influenced by allergen sensitization, and early intervention targeting IgE and IgE-mediated responses may help prevent and reduce the severity of asthma development.

CONTEMPORARY CLINICAL TRIALS (2021)

Correction Biochemistry & Molecular Biology

The basic immunology of asthma (vol 184, pg 1469, 2021)

Hamida Hammad et al.

Letter Critical Care Medicine

Fractional Exhaled Nitric Oxide Nonsuppression Identifies Corticosteroid-Resistant Type 2 Signaling in Severe Asthma

Simon Couillard et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2021)

Article Allergy

Allergen extract- and component-based diagnostics in children of the ALLIANCE asthma cohort

Chrysanthi Skevaki et al.

Summary: In this study, analytical and diagnostic concordance of three commonly used technologies for sIgE detection among young children was found to be good. Despite differences in positive concordance for common sensitizations, extending the number of allergens did not significantly change the overall performance of the three assay systems. These results suggest that more comprehensive multiplex approaches may not improve the clinical utility of sIgE testing in this age group.

CLINICAL AND EXPERIMENTAL ALLERGY (2021)

Article Respiratory System

Blood eosinophil count in the general population: typical values and potential confounders

Sylvia Hartl et al.

EUROPEAN RESPIRATORY JOURNAL (2020)

Article Allergy

Refractory airway type 2 inflammation in a large subgroup of asthmatic patients treated with inhaled corticosteroids

Michael C. Peters et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2019)

Article Allergy

Eosinophils capture viruses, a capacity that is defective in asthma

Yanaika S. Sabogal Pineros et al.

ALLERGY (2019)

Review Allergy

Phenotypes and endotypes of adult asthma: Moving toward precision medicine

Ravdeep Kaur et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2019)

Article Allergy

Single and multiple time-point allergic sensitization during childhood and risk of asthma by age 13

Ann-Marie Malby Schoos et al.

PEDIATRIC ALLERGY AND IMMUNOLOGY (2019)

Review Respiratory System

Severe T2-high asthma in the biologics era: European experts' opinion

Ian Pavord et al.

EUROPEAN RESPIRATORY REVIEW (2019)

Review Pediatrics

Severe Asthma-Perspectives From Adult and Pediatric Pulmonology

Louise Fleming et al.

FRONTIERS IN PEDIATRICS (2019)

Article Allergy

Sputum transcriptomics reveal upregulation of IL-1 receptor family members in patients with severe asthma

Christos Rossios et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2018)

Review Medicine, General & Internal

After asthma: redefining airways diseases

Ian D. Pavord et al.

LANCET (2018)

Article Allergy

Baseline Features of the Severe Asthma Research Program (SARP III) Cohort: Differences with Age

W. Gerald Teague et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2018)

Article Allergy

Identification of airway mucosal type 2 inflammation by using clinical biomarkers in asthmatic patients

Philip E. Silkoff et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2017)

Article Allergy

Latent class analysis reveals clinically relevant atopy phenotypes in 2 birth cohorts

Alexander J. Hose et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2017)

Article Allergy

Distinguishing benign from pathologic TH2 immunity in atopic children

Patrick G. Holt et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2016)

Article Allergy

Dissecting childhood asthma with nasal transcriptomics distinguishes subphenotypes of disease

Alex Poole et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2014)

Article Respiratory System

Multi-ethnic reference values for spirometry for the 3-95-yr age range: the global lung function 2012 equations

Philip H. Quanjer et al.

EUROPEAN RESPIRATORY JOURNAL (2012)

Article Critical Care Medicine

T-helper Type 2-driven Inflammation Defines Major Subphenotypes of Asthma

Prescott G. Woodruff et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2009)

Article Immunology

Eosinophils and their interactions with respiratory virus pathogens

Helene F. Rosenberg et al.

IMMUNOLOGIC RESEARCH (2009)

Article Critical Care Medicine

A clinical index to define risk of asthma in young children with recurrent wheezing

JA Castro-Rodríguez et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2000)