4.6 Article

Bio-physical and computational studies on serum albumin/target protein binding of a potential anti-cancer agent

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Chemistry, Medicinal

A Decade of FDA-Approved Drugs (2010-2019): Trends and Future Directions

Dean G. Brown et al.

Summary: Evaluation of 378 novel drugs and 27 biosimilars approved by the U.S. FDA between 2010 and 2019 revealed oncology as the top therapy area, potential increase in clinical development times, and rapid progress in innovation in new modalities.

JOURNAL OF MEDICINAL CHEMISTRY (2021)

Article Chemistry, Medicinal

US FDA Approved Drugs from 2015-June 2020: A Perspective

Priyadeep Bhutani et al.

Summary: This study compiled and analyzed 245 drugs approved by the U.S. FDA from 2015 to June 2020, focusing on cancer, infectious diseases, neurological conditions, and genetic, metabolic, cardiovascular disorders. The analysis also looked at the structural, elemental, and functional group diversity among the approved drugs, as well as drug-likeness for the approved drugs.

JOURNAL OF MEDICINAL CHEMISTRY (2021)

Article Chemistry, Multidisciplinary

Antiproliferative Activity of Some Newly Synthesized Substituted Pyridine Candidates Using 4-(Aaryl)-6-(naphthalen-1-yl)-2-oxo-1,2-dihydropyridine-3-carbonitrile as Synthon

Amira A. El-Sayed et al.

Summary: In this study, novel and active antineoplastic agents were synthesized using nicotinonitrile derivatives as scaffolds. These synthesized compounds exhibited potential cytotoxic effects against different cancer cell lines, with derivative 14a being the most effective against NCIH 460 and RKOP 27 cells.

ACS OMEGA (2021)

Article Biochemistry & Molecular Biology

Design, synthesis and docking study of pyridine and thieno[2,3-b] pyridine derivatives as anticancer PIM-1 kinase inhibitors

Marwa E. Abdelaziz et al.

BIOORGANIC CHEMISTRY (2018)

Article Chemistry, Medicinal

Eco-friendly synthesis of novel cyanopyridine derivatives and their anticancer and PIM-1 kinase inhibitory activities

Khaled A. M. Abouzid et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)

Article Biochemistry & Molecular Biology

Synthesis, characterization and serum albumin binding studies of vitamin K3 derivatives

Murugesan Suganthi et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2017)

Review Pharmacology & Pharmacy

Integrating Genomics into Drug Discovery and Development: Challenges and Aspirations

Rajiv Raja et al.

PHARMACEUTICAL MEDICINE (2017)

Article Medicine, Research & Experimental

Pim-1 kinase as cancer drug target: An update

Yernar Tursynbay et al.

BIOMEDICAL REPORTS (2016)

Review Pharmacology & Pharmacy

In vitro, in silico and integrated strategies for the estimation of plasma protein binding. A review

George Lambrinidis et al.

ADVANCED DRUG DELIVERY REVIEWS (2015)

Article Chemistry, Physical

Exploring the Interaction of Bisphenol-S with Serum Albumins: A Better or Worse Alternative for Bisphenol A?

Manjumol Mathew et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2014)

Review Chemistry, Medicinal

The PIM Family of Serine/Threonine Kinases in Cancer

Maja Narlik-Grassow et al.

MEDICINAL RESEARCH REVIEWS (2014)

Review Biochemistry & Molecular Biology

Albumin-drug interaction and its clinical implication

Keishi Yamasaki et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2013)

Article Biochemistry & Molecular Biology

Crystallographic studies of the complexes of bovine and equine serum albumin with 3,5-diiodosalicylic acid

Bartosz Sekula et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2013)

Article Chemistry, Physical

New Insight into Molecular Interactions of Imidazolium Ionic Liquids with Bovine Serum Albumin

Yang Shu et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2011)

Article Chemistry, Physical

Exploring the Mechanism of Fluorescence Quenching in Proteins Induced by Tetracycline

Uttam Anand et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2011)

Review Biochemical Research Methods

Drug-protein binding: a critical review of analytical tools

Karine Vuignier et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2010)

Article Biochemistry & Molecular Biology

Interactions between Antimalarial Indolone-N-oxide Derivatives and Human Serum Albumin

Nehal Ibrahim et al.

BIOMACROMOLECULES (2010)

Article Chemistry, Physical

Fluorescence resonance energy transfer from serum albumins to 1-anthracene sulphonate entrapped in reverse micellar nanocavities

Sayaree Dhar et al.

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS (2010)

Article Chemistry, Physical

Spectroscopic Probing of the Microenvironment in a Protein-Surfactant Assembly

Uttam Anand et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2010)

Article Biochemistry & Molecular Biology

Design, synthesis and biological evaluation of novel pyridine derivatives as anticancer agents and phosphodiesterase 3 inhibitors

Ashraf H. Abadi et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2009)

Article Chemistry, Physical

Photophysics of Backbone Fluorescent DNA Modifications: Reducing Uncertainties in FRET

Suman Ranjit et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2009)

Review Biochemistry & Molecular Biology

A survey of the year 2007 literature on applications of isothermal titration calorimetry

Sasa Bjelic et al.

JOURNAL OF MOLECULAR RECOGNITION (2008)

Review Chemistry, Medicinal

Raman spectroscopy of protein pharmaceuticals

Zai-Qing Wen

JOURNAL OF PHARMACEUTICAL SCIENCES (2007)

Article Chemistry, Medicinal

Identification and structure-activity relationships of substituted pyridones as inhibitors of Pim-1 kinase

I. Wayne Cheney et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)

Article Biochemistry & Molecular Biology

Structural basis of the drug-binding specificity of human serum albumin

J Ghuman et al.

JOURNAL OF MOLECULAR BIOLOGY (2005)

Review Biochemistry & Molecular Biology

New methodologies for measuring protein interactions in vivo and in vitro

J Piehler

CURRENT OPINION IN STRUCTURAL BIOLOGY (2005)

Article Biochemistry & Molecular Biology

PhotochemCAD 2: A Refined Program with Accompanying Spectral Databases for Photochemical Calculations

JM Dixon et al.

PHOTOCHEMISTRY AND PHOTOBIOLOGY (2005)

Article Chemistry, Medicinal

Glide: A new approach for rapid, accurate docking and scoring. 2. Enrichment factors in database screening

TA Halgren et al.

JOURNAL OF MEDICINAL CHEMISTRY (2004)

Article Chemistry, Medicinal

In silico prediction of drug-binding strengths to human serum albumin

G Colmenarejo

MEDICINAL RESEARCH REVIEWS (2003)

Review Chemistry, Physical

Raman Spectroscopy - A prospective tool in the life sciences

R Petry et al.

CHEMPHYSCHEM (2003)

Article Biochemistry & Molecular Biology

Study of protein-ligand binding by fluorescence

M Möller et al.

BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION (2002)

Article Biochemistry & Molecular Biology

The Protein Data Bank

HM Berman et al.

NUCLEIC ACIDS RESEARCH (2000)