Endocrine disrupting chemicals (EDCs) in environmental matrices: Occurrence, fate, health impact, physio-chemical and bioremediation technology

Endocrine disrupting chemicals (EDCs) are an emerging category of toxicity that adversely impacts humans and the environment's well-being. Diseases like cancer, cardiovascular risk, behavioral disorders, autoimmune defects, and reproductive diseases are related to these endocrine disruptors. Because these chemicals exist in known sources such as pharmaceuticals and plasticizers, as well as non-point sources such as agricultural runoff and storm water infiltration, the interactive effects of EDCs are gaining attention. However, the efficiency of conventional treatment methods is not sufficient to fully remediate EDCs from aqueous environments as the occurrence of EDC bioremediation and biodegradation is detected in remediated drinking water. Incorporating modification into current remediation techniques has to overcome challenges such as high energy consumption and health risks resulting from conventional treatment. Hence, the use of advanced psychochemical and bio-logical treatments such as carbon-based adsorption, membrane technology, nanostructured photocatalysts, microbial and enzyme technologies is crucial. Intensifying environmental and health concerns about these mixed contaminants are primarily due to the lack of laws about acute concentration limits of these EDCs in municipal wastewater, groundwater, surface water, and drinking water. This review article offers evidence of fragmentary available data for the source, fate, toxicity, ecological and human health impact, remediation techniques, and mechanisms during EDC removal, and supports the need for further data to address the risks associated with the presence of EDCs in the environment. The reviews also provide comprehensive data for biodegradation of EDCs by using microbes such as fungi, bacteria, yeast, filamentous fungi, and their extracellular enzymes.

Automated summary

Endocrine disrupting chemicals (EDCs) have adverse impacts on human and environmental well-being, being associated with diseases such as cancer, cardiovascular risk, behavioral disorders, autoimmune defects, and reproductive diseases. Conventional treatment methods are insufficient to fully remove EDCs from water, necessitating the use of advanced psychochemical and biological treatments. The lack of laws regarding acute concentration limits of EDCs in various water sources contributes to the intensified concerns about these mixed contaminants. Further data is needed to address the risks associated with the presence of EDCs in the environment.