4.7 Article

Physical and functional interactome atlas of human receptor tyrosine kinases

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Biochemistry & Molecular Biology

The LMTK-family of kinases: Emerging important players in cell physiology and pathogenesis

Franz Wendler et al.

Summary: LMTKs are a novel family of serine/threonine specific kinases with diverse functions in cell signaling, membrane trafficking, and gene regulation. They play crucial roles in cell proliferation, differentiation, migration, and are implicated in neuropathologies and tumorigenesis, with potential as drug targets for various diseases. Their primary role may lie in endocytic cargo recycling and/or nuclear receptor transport pathways.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2021)

Article Biochemistry & Molecular Biology

The BioGRID database: A comprehensive biomedical resource of curated protein, genetic, and chemical interactions

Rose Oughtred et al.

Summary: BioGRID is an open-access database resource that houses protein and genetic interactions from multiple species, serving as a tool for building complex networks to facilitate biomedical discoveries. Curated from primary experimental evidence, BioGRID captures both low-throughput and large high-throughput studies, including protein post-translational modifications and interactions with bioactive small molecules. Additionally, it undertakes themed curation projects in specific aspects of cellular regulation and disease areas.

PROTEIN SCIENCE (2021)

Article Microbiology

Activation of EphA2-EGFR signaling in oral epithelial cells by Candida albicans virulence factors

Marc Swidergall et al.

Summary: During oropharyngeal candidiasis, Candida albicans invades oral epithelial cells and triggers pro-inflammatory response. EphA2 detects beta-glucan and stimulates epithelial cells to release proinflammatory mediators. EGFR interacts with Candida albicans and is activated by Als3 adhesin/invasin and candidalysin pore-forming toxin. EphA2 and EGFR are part of a heteromeric complex and reliant on each other for Candida albicans-induced activation. Als3 enhances targeting of candidalysin, leading to maximal damage to oral epithelial cells and inflammatory cytokine secretion. Candidalysin and EGFR are required for CXCL1/KC and CCL20 production, while Als3 is necessary for TNF alpha but independent for IL-1 alpha and IL-17A. These results demonstrate the complex interplay among host cell receptors and virulence factors during OPC.

PLOS PATHOGENS (2021)

Article Biochemistry & Molecular Biology

Mapping the Phospho-dependent ALK Interactome to Identify Novel Components in ALK Signaling

Farzaneh Aboualizadeh et al.

Summary: This study systematically characterized the phospho-dependent ALK interactome using the MaMTH system, identifying 30 novel ALK interactors from a library of 86 SH2 domain-containing full length proteins. The interactions of these novel proteins are correlated to ALK phosphorylation activity and NCK2 was further validated as a key interactor in neuroblastoma cells. The study provides a valuable resource list of potential novel ALK signaling components for further exploration.

JOURNAL OF MOLECULAR BIOLOGY (2021)

Article Biochemistry & Molecular Biology

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome

Edward L. Huttlin et al.

Summary: This study explores thousands of interactions between proteins, creating two essential cell-line specific interaction networks that help researchers understand the principles of proteome organization and unknown protein characteristics. Comparing different cell lines revealed extensive customization, linking core complexes with essential proteins and rewiring subnetworks to produce each cell's phenotype.
Article Multidisciplinary Sciences

A proximity-dependent biotinylation map of a human cell

Christopher D. Go et al.

Summary: The study utilized BioID technology to construct a map of subcellular compartments in human cells, identifying the intracellular locations of numerous unique proteins and demonstrating the superior predictive ability of this technique compared to previous methods.

NATURE (2021)

Review Biochemistry & Molecular Biology

Tyrosine kinase signaling in and on the endoplasmic reticulum

Hesso Farhan

BIOCHEMICAL SOCIETY TRANSACTIONS (2020)

Article Biochemical Research Methods

SciPy 1.0: fundamental algorithms for scientific computing in Python

Pauli Virtanen et al.

NATURE METHODS (2020)

Review Cell Biology

Receptor tyrosine kinase activation: From the ligand perspective

Raphael Trenker et al.

CURRENT OPINION IN CELL BIOLOGY (2020)

Article Biochemical Research Methods

Fast Quantitative Analysis of timsTOF PASEF Data with MSFragger and IonQuant

Fengchao Yu et al.

MOLECULAR & CELLULAR PROTEOMICS (2020)

Article Biochemistry & Molecular Biology

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan et al.

MOLECULAR CELL (2020)

Article Biochemistry & Molecular Biology

The EMBL-EBI search and sequence analysis tools APIs in 2019

Fabio Madeira et al.

NUCLEIC ACIDS RESEARCH (2019)

Article Multidisciplinary Sciences

Large-scale Discovery of Substrates of the Human Kinome

Naoyuki Sugiyama et al.

SCIENTIFIC REPORTS (2019)

Review Biochemistry & Molecular Biology

Eph receptor signalling: from catalytic to non-catalytic functions

Lung-Yu Liang et al.

ONCOGENE (2019)

Review Chemistry, Multidisciplinary

The RTK Interactome: Overview and Perspective on RTK Heterointeractions

Michael D. Paul et al.

CHEMICAL REVIEWS (2019)

Article Biochemistry & Molecular Biology

CORUM: the comprehensive resource of mammalian protein complexes2019

Madalina Giurgiu et al.

NUCLEIC ACIDS RESEARCH (2019)

Article Biochemistry & Molecular Biology

The Pfam protein families database in 2019

Sara El-Gebali et al.

NUCLEIC ACIDS RESEARCH (2019)

Article Biochemistry & Molecular Biology

The Reactome Pathway Knowledgebase

Antonio Fabregat et al.

NUCLEIC ACIDS RESEARCH (2018)

Article Biochemistry & Molecular Biology

The human protein atlas: A spatial map of the human proteome

Peter J. Thul et al.

PROTEIN SCIENCE (2018)

Review Biochemistry & Molecular Biology

Receptor tyrosine kinases (RTKs) in breast cancer: signaling, therapeutic implications and challenges

Ramesh Butti et al.

MOLECULAR CANCER (2018)

Article Biochemistry & Molecular Biology

High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies

Ji-Young Youn et al.

MOLECULAR CELL (2018)

Article Biotechnology & Applied Microbiology

Efficient proximity labeling in living cells and organisms with TurboID

Tess C. Branon et al.

NATURE BIOTECHNOLOGY (2018)

Article Biochemical Research Methods

Online Parallel Accumulation Serial Fragmentation (PASEF) with a Novel Trapped on Mobility Mass Spectrometer

Florian Meier et al.

MOLECULAR & CELLULAR PROTEOMICS (2018)

Review Biochemistry & Molecular Biology

Interplay of autophagy, receptor tyrosine kinase signalling and endocytic trafficking

Jane Fraser et al.

SIGNALLING MECHANISMS IN AUTOPHAGY (2017)

Review Genetics & Heredity

PDGFs and their receptors

Andrius Kazlauskas

Article Biochemistry & Molecular Biology

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome

Zhong Yao et al.

MOLECULAR CELL (2017)

Article Biochemistry & Molecular Biology

Integration of over 9,000 mass spectrometry experiments builds a global map of human protein complexes

Kevin Drew et al.

MOLECULAR SYSTEMS BIOLOGY (2017)

Article Multidisciplinary Sciences

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin et al.

NATURE (2017)

Letter Biochemical Research Methods

ProHits-viz: a suite of web tools for visualizing interaction proteomics data

James D. R. Knight et al.

NATURE METHODS (2017)

Article Multidisciplinary Sciences

A pathology atlas of the human cancer transcriptome

Mathias Uhlen et al.

SCIENCE (2017)

Article Biochemistry & Molecular Biology

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics

Leena Yadav et al.

CELL SYSTEMS (2017)

Article Biochemistry & Molecular Biology

Determination of the catalytic activity of LEOPARD syndrome-associated SHP2 mutants toward parafibromin, a bona fide SHP2 substrate involved in Wnt signaling

Saori Noda et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)

Article Cell Biology

Signaling Receptors for TGF-β Family Members

Carl-Henrik Heldin et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2016)

Article Multidisciplinary Sciences

Identifying Kinase Substrates via a Heavy ATP Kinase Assay and Quantitative Mass Spectrometry

Andre C. Mueller et al.

SCIENTIFIC REPORTS (2016)

Review Biochemistry & Molecular Biology

Receptor tyrosine kinase mutations in developmental syndromes and cancer: two sides of the same coin

Laura M. McDonell et al.

HUMAN MOLECULAR GENETICS (2015)

Article Multidisciplinary Sciences

Tissue-based map of the human proteome

Mathias Uhlen et al.

SCIENCE (2015)

Article Biochemistry & Molecular Biology

PhosphoSitePlus, 2014: mutations, PTMs and recalibrations

Peter V. Hornbeck et al.

NUCLEIC ACIDS RESEARCH (2015)

Review Biochemistry & Molecular Biology

PDGF receptor signaling networks in normal and cancer cells

Jean-Baptiste Demoulin et al.

CYTOKINE & GROWTH FACTOR REVIEWS (2014)

Article Biochemistry & Molecular Biology

The MIntAct project-IntAct as a common curation platform for 11 molecular interaction databases

Sandra Orchard et al.

NUCLEIC ACIDS RESEARCH (2014)

Article Biochemistry & Molecular Biology

SH3 interactome conserves general function over specific form

Xiaofeng Xin et al.

MOLECULAR SYSTEMS BIOLOGY (2013)

Article Biochemical Research Methods

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MSMS

Markku Varjosalo et al.

NATURE METHODS (2013)

Article Biochemical Research Methods

The CRAPome: a contaminant repository for affinity purification-mass spectrometry data

Dattatreya Mellacheruvu et al.

NATURE METHODS (2013)

Review Cell Biology

Exploring mechanisms of FGF signalling through the lens of structural biology

Regina Goetz et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)

Article Cell Biology

Effects of Membrane Trafficking on Signaling by Receptor Tyrosine Kinases

Marta Miaczynska

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)

Article Cell Biology

Biological Function of Nuclear Receptor Tyrosine Kinase Action

Sungmin Song et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)

Article Cell Biology

The Protein Interaction Landscape of the Human CMGC Kinase Group

Markku Varjosalo et al.

CELL REPORTS (2013)

Article Biochemical Research Methods

Phosphotyrosine mediated protein interactions of the discoidin domain receptor 1

Simone Lemeer et al.

JOURNAL OF PROTEOMICS (2012)

Article Biochemistry & Molecular Biology

PINA v2.0: mining interactome modules

Mark J. Cowley et al.

NUCLEIC ACIDS RESEARCH (2012)

Article Biochemistry & Molecular Biology

The Eph-Receptor A7 Is a Soluble Tumor Suppressor for Follicular Lymphoma

Elisa Oricchio et al.

Article Cell Biology

Eph receptor function is modulated by heterooligomerization of A and B type Eph receptors

Peter W. Janes et al.

JOURNAL OF CELL BIOLOGY (2011)

Article Biochemical Research Methods

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

Juergen Cox et al.

JOURNAL OF PROTEOME RESEARCH (2011)

Article Biochemical Research Methods

SAINT: probabilistic scoring of affinity purification-mass spectrometry data

Hyungwon Choi et al.

NATURE METHODS (2011)

Article Biochemistry & Molecular Biology

Phospho.ELM: a database of phosphorylation sites-update 2011

Holger Dinkel et al.

NUCLEIC ACIDS RESEARCH (2011)

Article Biochemistry & Molecular Biology

Cell Signaling by Receptor Tyrosine Kinases

Mark A. Lemmon et al.

Article Multidisciplinary Sciences

COT drives resistance to RAF inhibition through MAP kinase pathway reactivation

Cory M. Johannessen et al.

NATURE (2010)

Review Cell Biology

Signalling ballet in space and time

Boris N. Kholodenko et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)

Review Oncology

Fibroblast growth factor signalling: from development to cancer

Nicholas Turner et al.

NATURE REVIEWS CANCER (2010)

Article Cell Biology

ErbB receptors and signaling pathways in cancer

Nancy E. Hynes et al.

CURRENT OPINION IN CELL BIOLOGY (2009)

Article Biochemistry & Molecular Biology

An integrated workflow for charting the human interaction proteome: insights into the PP2A system

Timo Glatter et al.

MOLECULAR SYSTEMS BIOLOGY (2009)

Article Biochemical Research Methods

A Novel Scoring Approach for Protein Co-Purification Data Reveals High Interaction Specificity

Xueping Yu et al.

PLOS COMPUTATIONAL BIOLOGY (2009)

Article Medicine, Research & Experimental

The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling

Dana M. Brantley-Sieders et al.

JOURNAL OF CLINICAL INVESTIGATION (2008)

Review Biochemistry & Molecular Biology

Regulation of MAPKs by growth factors and receptor tyrosine kinases

Menachem Katz et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2007)

Article Oncology

Activation of the EGFR gene target EphA2 inhibits epidermal growth factor-induced cancer cell motility

Alice Bjerregaard Larsen et al.

MOLECULAR CANCER RESEARCH (2007)

Review Biochemistry & Molecular Biology

The insulin and EGF receptor structures: new insights into ligand-induced receptor activation

Colin W. Ward et al.

TRENDS IN BIOCHEMICAL SCIENCES (2007)

Review Cell Biology

Protein tyrosine phosphatases: from genes, to function, to disease

Nicholas K. Tonks

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)

Review Biochemistry & Molecular Biology

Nuclear signaling by receptor tyrosine kinases: The first robin of spring

Joseph Schlessinger et al.

Review Cell Biology

Signaling through ERBB receptors: Multiple layers of diversity and control

CM Warren et al.

CELLULAR SIGNALLING (2006)

Article Oncology

The developing role of receptors and adaptors

C Massie et al.

NATURE REVIEWS CANCER (2006)

Review Cell Biology

EPH receptor signalling casts a wide net on cell behaviour

EB Pasquale

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)

Article Biochemistry & Molecular Biology

Cytokine and growth factor receptors in the nucleus: What's up with that?

JJ Krolewski

JOURNAL OF CELLULAR BIOCHEMISTRY (2005)

Article Endocrinology & Metabolism

The orphan receptor tyrosine kinase Ror2 modulates canonical Wnt signaling in osteoblastic cells

J Billiard et al.

MOLECULAR ENDOCRINOLOGY (2005)

Article Biochemistry & Molecular Biology

Nuclear trafficking of FGFR1: A role for the transmembrane domain

JM Myers et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Cytoscape: A software environment for integrated models of biomolecular interaction networks

P Shannon et al.

GENOME RESEARCH (2003)

Review Cell Biology

Regulation of receptor tyrosine kinase signaling by protein tyrosine phosphatases

A Östman et al.

TRENDS IN CELL BIOLOGY (2001)

Review Biochemistry & Molecular Biology

The protein tyrosine kinase family of the human genome

DR Robinson et al.

ONCOGENE (2000)