相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Difamilast, a selective phosphodiesterase 4 inhibitor, ointment in paediatric patients with atopic dermatitis: a phase III randomized double-blind, vehicle-controlled trial
H. Saeki et al.
BRITISH JOURNAL OF DERMATOLOGY (2022)
Atopic dermatitis: an expanding therapeutic pipeline for a complex disease
Thomas Bieber
NATURE REVIEWS DRUG DISCOVERY (2022)
Difamilast ointment in adult patients with atopic dermatitis: A phase 3 randomized, double-blind, vehicle-controlled trial
Hidehisa Saeki et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2022)
34794 Long-term safety and disease control of ruxolitinib cream among Black or African American patients with atopic dermatitis: Pooled results from 2 phase 3 studies
Lawrence F. Eichenfield et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2022)
Phase 2 randomized, double-blind study of IL-17 targeting with secukinumab in atopic dermatitis
Benjamin Ungar et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2021)
Efficacy and patient-reported outcomes from a phase 2b, randomized clinical trial of tapinarof cream for the treatment of adolescents and adults with atopic dermatitis
Amy S. Paller et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2021)
Atopic dermatitis in the pediatric population A cross-sectional, international epidemiologic study
Jonathan Silverberg et al.
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY (2021)
JAK1/2 inhibition impairs the development and function of inflammatory dendritic epidermal cells in atopic dermatitis
Anna Sophie Klaeschen et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2021)
A Phase 1b, Randomized, Single-Center Trial of Topical Cerdulatinib (DMVT-502) in Patients with Mild-to-Moderate Atopic Dermatitis
[Anonymous]
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2021)
Delgocitinib ointment in pediatric patients with atopic dermatitis: A phase 3, randomized, double-blind, vehicle-controlled study and a subsequent open-label, long-term study
Hidemi Nakagawa et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2021)
Development of a human skin commensal microbe for bacteriotherapy of atopic dermatitis and use in a phase 1 randomized clinical trial
Teruaki Nakatsuji et al.
NATURE MEDICINE (2021)
Long-term improvement of psoriasis patients' adherence to topical drugs: testing a patient-supporting intervention delivered by healthcare professionals
Mathias Tiedemann Svendsen et al.
TRIALS (2021)
Role of AHR Ligands in Skin Homeostasis and Cutaneous Inflammation
Nieves Fernandez-Gallego et al.
CELLS (2021)
Efficacy and safety of ruxolitinib cream for the treatment of atopic dermatitis: Results from 2 phase 3, randomized, double-blind studies
Kim Papp et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2021)
Efficacy and safety of topical Janus kinase and phosphodiesterase inhibitor-4 inhibitors for the treatment of atopic dermatitis: A network meta-analysis
Lu Zhang et al.
JOURNAL OF DERMATOLOGY (2021)
28194 Patient-reported outcomes of ruxolitinib cream for the treatment of atopic dermatitis: Pooled results from two phase 3 studies
Eric L. Simpson et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2021)
Skin microbiome transplantation and manipulation: Current state of the art
Chris Callewaert et al.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2021)
Efficacy and safety of topical delgocitinib in patients with chronic hand eczema: data from a randomized, double-blind, vehicle-controlled phase IIa study
M. Worm et al.
BRITISH JOURNAL OF DERMATOLOGY (2020)
The role of AhR in transcriptional regulation of immune cell development and function
Prashant Trikha et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2020)
Janus kinase inhibitor delgocitinib suppresses pruritus and nerve elongation in an atopic dermatitis murine model
Yasuo Yamamoto et al.
JOURNAL OF DERMATOLOGICAL SCIENCE (2020)
Delgocitinib ointment, a topical Janus kinase inhibitor, in adult patients with moderate to severe atopic dermatitis: A phase 3, randomized, double-blind, vehicle-controlled study and an open-label, long-term extension study
Hidemi Nakagawa et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2020)
Safety, Effectiveness, and Pharmacokinetics of Crisaborole in Infants Aged 3 to < 24 Months with Mild-to-Moderate Atopic Dermatitis: A Phase IV Open-Label Study (CrisADe CARE 1)
Joel Schlessinger et al.
AMERICAN JOURNAL OF CLINICAL DERMATOLOGY (2020)
Pharmacodynamic Effects of Topical Omiganan in Patients With Mild to Moderate Atopic Dermatitis in a Randomized, Placebo-Controlled, Phase II Trial
Tessa Niemeyer-van der Kolk et al.
CTS-CLINICAL AND TRANSLATIONAL SCIENCE (2020)
No evidence of increased cancer incidence in children using topical tacrolimus for atopic dermatitis
Amy S. Paller et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2020)
Therapeutic responses to Roseomonas mucosa in atopic dermatitis may involve lipid-mediated TNF-related epithelial repair
Ian A. Myles et al.
SCIENCE TRANSLATIONAL MEDICINE (2020)
16089 Safety of ATI-502, a novel topical JAK1/3 inhibitor, in adults with moderate to severe atopic dermatitis: Results from a phase 2a open-label trial
Stacy Smith et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2020)
A phase 2, randomized dose-finding study of tapinarof (GSK2894512 cream) for the treatment of atopic dermatitis
Johnny Peppers et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2019)
A systematic review and meta-analysis of the regional and age-related differences in atopic dermatitis clinical characteristics
Yik Weng Yew et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2019)
Comorbidities and the impact of atopic dermatitis
Jonathan I. Silverberg
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY (2019)
Microbiome therapeutics go small molecule
Megan Cully
NATURE REVIEWS DRUG DISCOVERY (2019)
The microbiome in patients with atopic dermatitis
Amy S. Paller et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2019)
Atopic dermatitis endotypes and implications for targeted therapeutics
Tali Czarnowicki et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2019)
A Phase 2 Randomized Trial of Apremilast in Patients with Atopic Dermatitis
Eric L. Simpson et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2019)
Measurement Properties of the Hospital Anxiety and Depression Scale Used in Atopic Dermatitis in Adults
Jonathan I. Silverberg et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2019)
A retrospective study: Application site pain with the use of crisaborole, a topical phosphodiesterase 4 inhibitor
Christine Pao-Ling Lin et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2019)
Atopic dermatitis yardstick: Practical recommendations for an evolving therapeutic landscape
Mark Boguniewicz et al.
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY (2018)
Atopic dermatitis
Stephan Weidinger et al.
NATURE REVIEWS DISEASE PRIMERS (2018)
Itch: From mechanism to (novel) therapeutic approaches
Gil Yosipovitch et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2018)
The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin
Takanori Hidaka et al.
NATURE IMMUNOLOGY (2017)
Molecular signatures order the potency of topically applied anti-inflammatory drugs in patients with atopic dermatitis
Emma Guttman-Yassky et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2017)
Therapeutic pipeline for atopic dermatitis: End of the drought?
Amy S. Paller et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2017)
Tapinarof Is a Natural AhR Agonist that Resolves Skin Inflammation in Mice and Humans
Susan H. Smith et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2017)
Janus kinase inhibitors in dermatology: A systematic review
Rony Shreberk-Hassidim et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2017)
Long-term management of moderate-to-severe atopic dermatitis with dupilumab and concomitant topical corticosteroids (LIBERTY AD CHRONOS): a 1-year, randomised, double-blinded, placebo-controlled, phase 3 trial
Andrew Blauvelt et al.
LANCET (2017)
Antimicrobials from human skin commensal bacteria protect against Staphylococcus aureus and are deficient in atopic dermatitis
Teruaki Nakatsuji et al.
SCIENCE TRANSLATIONAL MEDICINE (2017)
Dual SYK/JAK inhibition overcomes ibrutinib resistance in chronic lymphocytic leukemia: Cerdulatinib, but not ibrutinib, induces apoptosis of tumor cells protected by the microenvironment
Ailin Guo et al.
ONCOTARGET (2017)
Increasing Adherence with Topical Agents for Atopic Dermatitis
Nupur U. Patel et al.
AMERICAN JOURNAL OF CLINICAL DERMATOLOGY (2017)
Mechanisms and consequences of Jak-STAT signaling in the immune system
Alejandro V. Villarino et al.
NATURE IMMUNOLOGY (2017)
Effect of topical phosphodiesterase 4 inhibitor E6005 on Japanese children with atopic dermatitis: Results from a randomized, vehicle-controlled exploratory trial
Osamu Nemoto et al.
JOURNAL OF DERMATOLOGY (2016)
Targeting key proximal drivers of type 2 inflammation in disease
Namita A. Gandhi et al.
NATURE REVIEWS DRUG DISCOVERY (2016)
Systematic review of published trials: long-term safety of topical corticosteroids and topical calcineurin inhibitors in pediatric patients with atopic dermatitis
Elaine C. Siegfried et al.
BMC PEDIATRICS (2016)
Topical tofacitinib for atopic dermatitis: a phase IIa randomized trial
R. Bissonnette et al.
BRITISH JOURNAL OF DERMATOLOGY (2016)
Efficacy and Safety of Crisaborole Topical Ointment, 2%, a Novel, Nonsteroidal, Topical, Anti-Inflammatory, Phosphodiesterase Inhibitor in 2 Phase 3 Studies in Children and Adults with Mild-to-Moderate Atopic Dermatitis
Mark Boguniewicz et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2016)
Petrolatum: Barrier repair and antimicrobial responses underlying this inert moisturizer
Tali Czarnowicki et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2016)
Efficacy and safety of crisaborole ointment, a novel, nonsteroidal phosphodiesterase 4 (PDE4) inhibitor for the topical treatment of atopic dermatitis (AD) in children and adults
Amy S. Paller et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2016)
Update on Epidemiology, Diagnosis, and Disease Course of Atopic Dermatitis
Eric L. Simpson et al.
SEMINARS IN CUTANEOUS MEDICINE AND SURGERY (2016)
Safety and efficacy of topical E6005, a phosphodiesterase 4 inhibitor, in Japanese adult patients with atopic dermatitis: Results of a randomized, vehicle-controlled, multicenter clinical trial
Masutaka Furue et al.
JOURNAL OF DERMATOLOGY (2014)
Discovery and Early Clinical Development of 2-{6-[2-(3,5-Dichloro-4-pyridyl)acetyl]-2,3-dimethoxyphenoxy}-N-propylacetamide (LEO 29102), a Soft-Drug Inhibitor of Phosphodiesterase 4 for Topical Treatment of Atopic Dermatitis
Jakob Felding et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Guidelines of care for the management of atopic dermatitis Section 2. Management and treatment of atopic dermatitis with topical therapies
Lawrence F. Eichenfield et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2014)
Janus kinase inhibitors in autoimmune diseases
John J. O'Shea et al.
ANNALS OF THE RHEUMATIC DISEASES (2013)
Coal tar induces AHR-dependent skin barrier repair in atopic dermatitis
Ellen H. van den Bogaard et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Temporal shifts in the skin microbiome associated with disease flares and treatment in children with atopic dermatitis
Heidi H. Kong et al.
GENOME RESEARCH (2012)
Modulation of Innate and Adaptive Immune Responses by Tofacitinib (CP-690,550)
Kamran Ghoreschi et al.
JOURNAL OF IMMUNOLOGY (2011)
Nerve Growth Factor Partially Recovers Inflamed Skin from Stress-Induced Worsening in Allergic Inflammation
Eva M. J. Peters et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2011)
Thymic stromal lymphopoietin-mediated STAT5 phosphorylation via kinases JAK1 and JAK2 reveals a key difference from IL-7-induced signaling
Yrina Rochman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Atopic Dermatitis: A Disease Caused by Innate Immune Defects?
Anna De Benedetto et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2009)
A systematic review of the safety of topical therapies for atopic dermatitis
J. Callen et al.
BRITISH JOURNAL OF DERMATOLOGY (2007)
IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes
K Boniface et al.
JOURNAL OF IMMUNOLOGY (2005)
Endogenous antimicrobial peptides and skin infections in atopic dermatitis
PY Ong et al.
NEW ENGLAND JOURNAL OF MEDICINE (2002)
分享论文
