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Differential regulation of sinusoidal and canalicular hepatic drug transporter expression by xenobiotics activating drug-sensing receptors in primary human hepatocytes
Emilie Jigorel et al.
DRUG METABOLISM AND DISPOSITION (2006)
Regulation of the expression of human organic anion transporter 3 by hepatocyte nuclear factor 1 α/β and DNA methylation
Ryota Kikuchi et al.
MOLECULAR PHARMACOLOGY (2006)
Alterations in trans porter expression in liver, kidney, and duodenum after targeted disruption of the transcription factor HNF1α
J. M. Maher et al.
BIOCHEMICAL PHARMACOLOGY (2006)
The transcription factor Cdx2 regulates the intestine-specific expression of human peptide transporter 1 through functional interaction with Sp1
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BIOCHEMICAL PHARMACOLOGY (2006)
The human organic cation transporter-1 gene is transactivated by hepatocyte nuclear factor-4α
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JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
Farnesoid X receptor, hepatocyte nuclear factors 1α and 3β are essential for transcriptional activation of the liver-specific organic anion transporter-2 gene
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JOURNAL OF GASTROENTEROLOGY (2006)
Androgen receptor is responsible for rat organic cation transporter 2 gene regulation but not for rOCT1 and rOCT3
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PHARMACEUTICAL RESEARCH (2006)
Expression of the steroid and xenobiotic receptor and its possible target gene, organic anion transporting polypeptide-A, in human breast carcinoma
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CANCER RESEARCH (2006)
Regulation of mouse organic anion-transporting polypeptides (Oatps) in liver by prototypical microsomal enzyme inducers that activate distinct transcription factor pathways
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DRUG METABOLISM AND DISPOSITION (2005)
The human organic anion transporter 2 gene is transactivated by hepatocyte nuclear factor-4α and suppressed by bile acids
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MOLECULAR PHARMACOLOGY (2005)
The pregnane X receptor regulates gene expression in a ligand- and promoter-selective fashion
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MOLECULAR ENDOCRINOLOGY (2005)
Characterization of the human peptide transporter PEPT1 promoter: Sp1 functions as a basal transcriptional regulator of human PEPT1
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AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2005)
Down-regulation of the organic cation transporter 1 of rat liver in obstructive cholestasis
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HEPATOLOGY (2004)
The human organic anion transporting polypeptide 8 (SLCO1B3) gene is transcriptionally repressed by hepatocyte nuclear factor 3β in hepatocellular carcinoma
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JOURNAL OF HEPATOLOGY (2004)
The ABCs of solute carriers: physiological, pathological and therapeutic implications of human membrane transport proteins - Introduction
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PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2004)
Enterohepatic bile salt transporters in normal physiology and liver disease
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GASTROENTEROLOGY (2004)
Effects of proinflammatory cytokines on rat organic anion transporters during toxic liver injury and cholestasis
A Geier et al.
HEPATOLOGY (2003)
Human organic anion transporting polypeptide 8 promoter is transactivated by the farnesoid X receptor/bile acid receptor
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GASTROENTEROLOGY (2002)
Induction of rat organic anion transporting polypeptide 2 by pregnenolone-16α-carbonitrile is via interaction with pregnane X receptor
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MOLECULAR PHARMACOLOGY (2002)
Induction profile of rat organic anion transporting polypeptide 2 (oatp2) by prototypical drug-metabolizing enzyme inducers that activate gene expression through ligand-activated transcription factor pathways
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JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2002)
Characterization of the human OATP-C (SLC21A6) gene promoter and regulation of liver-specific OATP genes by hepatocyte nuclear factor 1α
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Effect of phenobarbital on the expression of bile salt and organic anion transporters of rat liver
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JOURNAL OF HEPATOLOGY (2001)
The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: Two mechanisms for repression
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MOLECULAR AND CELLULAR BIOLOGY (2000)
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