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Differential regulation of sinusoidal and canalicular hepatic drug transporter expression by xenobiotics activating drug-sensing receptors in primary human hepatocytes
Emilie Jigorel et al.
DRUG METABOLISM AND DISPOSITION (2006)
Regulation of the expression of human organic anion transporter 3 by hepatocyte nuclear factor 1 α/β and DNA methylation
Ryota Kikuchi et al.
MOLECULAR PHARMACOLOGY (2006)
Alterations in trans porter expression in liver, kidney, and duodenum after targeted disruption of the transcription factor HNF1α
J. M. Maher et al.
BIOCHEMICAL PHARMACOLOGY (2006)
The transcription factor Cdx2 regulates the intestine-specific expression of human peptide transporter 1 through functional interaction with Sp1
Jin Shimakura et al.
BIOCHEMICAL PHARMACOLOGY (2006)
The human organic cation transporter-1 gene is transactivated by hepatocyte nuclear factor-4α
M Saborowski et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
Farnesoid X receptor, hepatocyte nuclear factors 1α and 3β are essential for transcriptional activation of the liver-specific organic anion transporter-2 gene
H Ohtsuka et al.
JOURNAL OF GASTROENTEROLOGY (2006)
Androgen receptor is responsible for rat organic cation transporter 2 gene regulation but not for rOCT1 and rOCT3
J Asaka et al.
PHARMACEUTICAL RESEARCH (2006)
Expression of the steroid and xenobiotic receptor and its possible target gene, organic anion transporting polypeptide-A, in human breast carcinoma
Y Miki et al.
CANCER RESEARCH (2006)
Regulation of mouse organic anion-transporting polypeptides (Oatps) in liver by prototypical microsomal enzyme inducers that activate distinct transcription factor pathways
XG Cheng et al.
DRUG METABOLISM AND DISPOSITION (2005)
The human organic anion transporter 2 gene is transactivated by hepatocyte nuclear factor-4α and suppressed by bile acids
K Popowski et al.
MOLECULAR PHARMACOLOGY (2005)
The pregnane X receptor regulates gene expression in a ligand- and promoter-selective fashion
H Masuyama et al.
MOLECULAR ENDOCRINOLOGY (2005)
Characterization of the human peptide transporter PEPT1 promoter: Sp1 functions as a basal transcriptional regulator of human PEPT1
J Shimakura et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2005)
Down-regulation of the organic cation transporter 1 of rat liver in obstructive cholestasis
GU Denk et al.
HEPATOLOGY (2004)
The human organic anion transporting polypeptide 8 (SLCO1B3) gene is transcriptionally repressed by hepatocyte nuclear factor 3β in hepatocellular carcinoma
SR Vavricka et al.
JOURNAL OF HEPATOLOGY (2004)
The ABCs of solute carriers: physiological, pathological and therapeutic implications of human membrane transport proteins - Introduction
MA Hediger et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2004)
Enterohepatic bile salt transporters in normal physiology and liver disease
GA Kullak-Ublick et al.
GASTROENTEROLOGY (2004)
Effects of proinflammatory cytokines on rat organic anion transporters during toxic liver injury and cholestasis
A Geier et al.
HEPATOLOGY (2003)
Human organic anion transporting polypeptide 8 promoter is transactivated by the farnesoid X receptor/bile acid receptor
D Jung et al.
GASTROENTEROLOGY (2002)
Induction of rat organic anion transporting polypeptide 2 by pregnenolone-16α-carbonitrile is via interaction with pregnane X receptor
GL Guo et al.
MOLECULAR PHARMACOLOGY (2002)
Induction profile of rat organic anion transporting polypeptide 2 (oatp2) by prototypical drug-metabolizing enzyme inducers that activate gene expression through ligand-activated transcription factor pathways
GL Guo et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2002)
Characterization of the human OATP-C (SLC21A6) gene promoter and regulation of liver-specific OATP genes by hepatocyte nuclear factor 1α
D Jung et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Effect of phenobarbital on the expression of bile salt and organic anion transporters of rat liver
N Hagenbuch et al.
JOURNAL OF HEPATOLOGY (2001)
The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: Two mechanisms for repression
YK Lee et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)