期刊
DRUG DISCOVERY TODAY
卷 27, 期 8, 页码 2043-2050出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.drudis.2022.03.007
关键词
Anticancer; Bacterial-mediated; Tumor targeting; Payload delivery; Engineered bacteria; Tumor microenvironment
资金
- Masonic Medical Research Institute, Utica, New York
- USA for 2021 Halfond-Weil Postdoctoral Award
- University of Waterloo, Canada
Cancer treatments have improved significantly, but there is still room for improvement. In recent years, bacteria-based cancer therapy has gained attention for its unique properties, as bacteria can control tumor growth and improve prognosis.
Cancer treatments have advanced considerably in recent years, appreciably enhancing the quality of life and survival of cancer patients. However, standard cancer treatments still have limitations that must be improved. In recent years, bacteria-based cancer therapy has gained much more attention owing to its unique properties that are unachievable with standard therapeutics. Bacteria species such as Salmonella, Clostridium, and Listeria have been shown to control tumor growth with improved prognosis in experimental animal models and clinical settings.
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