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Bacterial cancer therapy: A turning point for new paradigms

期刊

DRUG DISCOVERY TODAY
卷 27, 期 8, 页码 2043-2050

出版社

ELSEVIER SCI LTD
DOI: 10.1016/j.drudis.2022.03.007

关键词

Anticancer; Bacterial-mediated; Tumor targeting; Payload delivery; Engineered bacteria; Tumor microenvironment

资金

  1. Masonic Medical Research Institute, Utica, New York
  2. USA for 2021 Halfond-Weil Postdoctoral Award
  3. University of Waterloo, Canada

向作者/读者索取更多资源

Cancer treatments have improved significantly, but there is still room for improvement. In recent years, bacteria-based cancer therapy has gained attention for its unique properties, as bacteria can control tumor growth and improve prognosis.
Cancer treatments have advanced considerably in recent years, appreciably enhancing the quality of life and survival of cancer patients. However, standard cancer treatments still have limitations that must be improved. In recent years, bacteria-based cancer therapy has gained much more attention owing to its unique properties that are unachievable with standard therapeutics. Bacteria species such as Salmonella, Clostridium, and Listeria have been shown to control tumor growth with improved prognosis in experimental animal models and clinical settings.

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