期刊
DRUG DISCOVERY TODAY
卷 27, 期 10, 页码 -出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.drudis.2022.05.023
关键词
Cancer; Bacteria; Cancer bacteriotherapy; Immunotherapy; Bibliometric analysis
资金
- Food and Drug Administration, National Institutes of Health [1R01FD007456-01]
This study conducted a global bibliometric analysis of the literature on bacteria-mediated cancer therapy from 2012 to 2021, using VOSviewer, CiteSpace, and Python. The analysis revealed that East Asia and North America contributed the most publications in this research area. The keyword analysis identified immunotherapy and nanoparticle-based drug delivery systems as popular topics, while the gut microbiota and probiotics emerged as research hotspots.
Bacteriotherapy has proved to be a powerful tool to fight against cancer. Herein, we used VOSviewer, CiteSpace, and Python to perform the first global bibliometric analysis of the literature from 2012 to 2021 on bacteria-mediated cancer therapy. Based on the results, East Asia and North America contributed the most publications to this research area. Additionally, the keyword analysis indicated that immunotherapy and nanoparticle (NP)-based drug delivery systems have long been popular topics in cancer bacteriotherapy, whereas the gut microbiota and probiotics are emerging research hotspots. This study provides crucial insights into the historical development of bacteria-mediated cancer therapy from 2012 to 2021, which will be helpful for scientists to conduct further investigation into this promising field.
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