4.3 Article

Evaluation of Toxoplasma gondii recombinant antigens for early diagnosis of congenital toxoplasmosis

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ELSEVIER SCIENCE INC
DOI: 10.1016/j.diagmicrobio.2021.115608

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Toxoplasmosis; Diagnosis; Congenital infection; Recombinant antigen; Serology

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  1. Agencia Nacional de Promocion Cientifica y Tecnologica (ANPCyT) [PIDC 0025]

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The performance of Toxoplasma rGra8, rMic1, and the chimeric rGra4-Gra7 antigens for early congenital toxoplasmosis (CT) diagnosis was evaluated. Sera from CT patients showed high IgG reactivity to rMic1, rGra8, and rGra4-Gra7. The seroreactivity of samples from uninfected infants was lost within 2 months of age.
The performance of Toxoplasma rGra8, rMic1, and the chimeric rGra4-Gra7 antigens for early congenital toxoplasmosis (CT) diagnosis was evaluated. Sera from CT patients showed high IgG reactivity to rMic1, rGra8, and rGra4-Gra7. The seroreactivity of samples from uninfected infants was lost within 2 months of age. (C) 2021 Published by Elsevier Inc.

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