Mapping the non-pregnant uterus cell-by-cell

The endometrium is a dynamic, multicellular tissue that is constantly remodeled in response to regulating hormones. In a recent issue of Nature Genetics, Garcia-Alonso et al. delineate the unique genetic signatures of the endometrial cells. Their findings validate a three-dimensional epithelial organoid system for modeling endometrial glands ex utero.

Automated summary

This study identifies the unique genetic signatures of endometrial cells and validates a three-dimensional epithelial organoid system for modeling endometrial glands ex utero.