期刊
CURRENT OPINION IN BIOTECHNOLOGY
卷 74, 期 -, 页码 211-219出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.copbio.2021.11.011
关键词
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Bioelectrosynthesis (BES) systems utilize extracellular electron transport pathways to enhance cellular metabolism, improving economic viability and reducing carbon footprint in biomanufacturing processes. To efficiently channel electrons towards biosynthesis, a better understanding of electron transport mechanisms and comprehensive evaluation of process performance is necessary.
Bioelectrosynthesis (BES) systems exploit extracellular electron transport pathways to augment cellular metabolism. This strategy can be used to improve the economic viability of bio-based syntheses versus conventional methods, most notably petrochemical-based syntheses. It also has the potential to reduce the carbon footprint of biomanufacturing processes. Efficient channeling of cathode-derived electrons towards biosynthesis requires a better understanding of the biological mechanisms of electron transport as well as detailed evaluation of all aspects of process performance. More advanced solutions may deploy cell free systems that use ex situ generated reducing equivalents to improve economic performance.
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