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Review
Neurosciences
Carly L. Clayman et al.
Summary: This study examines the neuropharmacological and behavioral consequences of caffeine and alcohol exposure in zebrafish model, highlighting the potential of alcohol as an anxiolytic substance that could offset the anxiogenic effects of caffeine and affect neural circuit development.
CURRENT NEUROPHARMACOLOGY
(2022)
Review
Neurosciences
Radharani Benvenutti et al.
Summary: This review integrates the major findings from zebrafish literature regarding the behavioral effects of NMDAR antagonists relevant to schizophrenia, suggesting that zebrafish is a suitable model organism for studying drug-induced behavioral phenotypes. However, more studies are needed to further understand the behavioral differences compared to mammals.
CURRENT NEUROPHARMACOLOGY
(2022)
Review
Neurosciences
Flavia Gheller Schaidhauer et al.
Summary: This article reviews studies that use zebrafish as a model to investigate the behavioral effects of early alcohol exposure. The findings suggest that zebrafish can be used to study the behavioral impairments associated with fetal alcohol syndrome. This is important for understanding the pathophysiological and behavioral consequences of early alcohol exposure.
CURRENT NEUROPHARMACOLOGY
(2022)
Review
Neurosciences
Fabiano Costa et al.
Summary: This article introduces the advantages of zebrafish as a pain model and its applications in studying the mechanisms of pain response. The article also discusses the latest research advances and outlines the potential advantages and limitations of zebrafish models in studying pain behaviors and mood disorders, as well as facilitating analgesic therapy screening.
CURRENT NEUROPHARMACOLOGY
(2022)
Review
Neurosciences
Maria P. Faillace et al.
Summary: Nicotine induces long-term changes in neural activity through epigenetic regulation, suggesting potential therapeutic interventions for nicotine addiction.
CURRENT NEUROPHARMACOLOGY
(2022)
Review
Neurosciences
Stefani Altenhofen et al.
Summary: Sleep is a crucial biological necessity for learning and memory consolidation, and the brain shows different types of electrical activity during sleep. The synaptic homeostasis theory suggests that sleep plays a role in restoring synaptic strength, which is disrupted by learning and synaptogenesis. Zebrafish, although lacking the division of sleep into REM and NREM states, have been used as a promising model to investigate sleep mechanisms and their regulation.
CURRENT NEUROPHARMACOLOGY
(2022)
Review
Neurosciences
Murilo S. de Abreu et al.
Summary: Although traditional medicine has been practiced for a long time, its therapeutic mechanisms are not fully understood. This study highlights the importance of using zebrafish as a model organism to study the neurotropic effects of traditional medicine and their potential in treating brain disorders.
CURRENT NEUROPHARMACOLOGY
(2022)
Review
Neurosciences
Keturah Kiper et al.
Summary: The prevalence of neurodegenerative diseases, such as Alzheimer's disease, is increasing globally. While rodent models are commonly used in research, their limitations highlight the need for alternative animal models. Zebrafish, with its advantages of low cost, small size, sequenced genome, well-characterized anatomy, and conservation of molecular function and disease pathways, has become a valuable tool in investigating Alzheimer's disease.
CURRENT NEUROPHARMACOLOGY
(2022)
Review
Behavioral Sciences
Robert Gerlai
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2020)
Review
Neurosciences
Barbara D. Fontana et al.
EXPERIMENTAL NEUROLOGY
(2018)
Article
Multidisciplinary Sciences
Kerstin Howe et al.