期刊
CURRENT MEDICINAL CHEMISTRY
卷 29, 期 30, 页码 5076-5096出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/0929867329666220328123953
关键词
Seven-membered ring; heterocyclic compounds; biological activities; antitumor; antisepsis; anti-inflammation
资金
- National Natural Science Foundation of China [21072131]
- Sichuan University-Lu Zhou Strategic Cooperation Projects [2017, CDLZ-S34]
This article summarizes the research advances in different kinds of seven-membered heterocyclic compounds containing nitrogen, oxygen, and sulfur heteroatoms with antitumor, antisepsis, and anti-inflammation activities in the past ten years, which are expected to be beneficial to the development and design of novel drugs for the corresponding indications.
Seven-membered heterocyclic compounds are important drug scaffolds because of their unique chemical structures. They widely exist in natural products and show a variety of biological activities. They have been used commonly in central nervous system drugs in the past 30 years. In the past decade, many studies have been conducted on their activities, including antitumor, antibacterial, etc. Herein, we summarize the research advances in different kinds of seven-membered heterocyclic compounds containing nitrogen, oxygen, and sulfur heteroatoms with antitumor, antisepsis, and anti-inflammation activities in the past ten years, which are expected to be beneficial to the development and design of novel drugs for the corresponding indications.
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