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Dietary acid load and cardiovascular diseases

期刊

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
卷 63, 期 28, 页码 9033-9038

出版社

TAYLOR & FRANCIS INC
DOI: 10.1080/10408398.2022.2066063

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dietary acid load; metabolic acidosis; cardiovascular disease

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Dietary acid load has an impact on cardiovascular diseases, but the research on this topic is limited and inconsistent. Possible mechanisms include excessive calcium and magnesium excretion, reduced urinary citrate excretion, and excessive cortisol production. Further studies are needed to explore the relationship between dietary acid load and cardiovascular diseases.
Diet affects the body's acid-base balance by providing acid or alkali precursors in the metabolism. The importance of the acid-base balance of the diet for cardiovascular diseases, which have become the most important cause of morbidity on the global scale, has started to take its place in the literature. The prediction of endogenous acid production in dietary acid-base balance is expressed as dietary acid load. Although the available information about the effect of dietary acid load on cardiovascular diseases is limited, possible mechanisms are indicated as excessive calcium and magnesium excretion from the kidneys, reduced urinary citrate excretion, and excessive cortisol production. Metabolic acidosis has an important role in the development of cardiometabolic abnormalities, especially insulin resistance. Studies examining the relationship between dietary acid load and cardiovascular disease are limited and there is an inconsistency between studies. Practices for determining risk factors for cardiovascular diseases and preventing their effects are very important for the protection and improvement of health. Considering dietary acid load when planning a diet for individuals with cardiovascular diseases can help increase the effectiveness of the diet. The purpose of this review is to examine the effect of dietary acid load on cardiovascular diseases.

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