Functional modification of polydimethylsiloxane nanocomposite with silver nanoparticles-based montmorillonite for antibacterial applications

The functionalization of polydimethylsiloxane (PDMS) nanocomposites with advanced nanostructure materials suggests that tailored control and objective design would create significant stages with improved mechanical properties and antimicrobial properties. This work designs a creative and easy technique for the binding of silver nanoparticles-lecithin modified montmorillonite (AgNPs@LEC-Mt) in PDMS nanocomposite for antibacterial Applications. The PDMS/ AgNPs@LEC-Mt nanocomposite was evaluated by XRD, FTIR, SEM and TEM analyses. PDMS/ AgNPs @LEC-Mt nanocomposites showed better thermal stability than pure PDMS by thermogravimetric analysis. The effect of AgNPs @ LEC-Mt on the mechanical properties of PDMS was studied. The mechanical property was the best among four of them when the content of AgNPs @ LEC-Mt within reaches 1%. PDMS / AgNPs @ LEC-Mt nanocomposites showed high antimicrobial activity against E. coli and S. aureus. In vitro experiments (cell experiments) and in vivo experiments (animal experiments) evaluated that PDMS/ AgNPs @LEC-Mt nanocomposites had excellent biocompatibility. The effortlessness of the procedure, the quick response time and the better antibacterial property is useful for the advancement of antimicrobial PDMS nanocomposites for medical antibacterial devices.

Automated summary

Functionalization of polydimethylsiloxane nanocomposites with advanced nanostructure materials can lead to significant improvements in mechanical and antimicrobial properties. This research presents a creative and easy technique for incorporating silver nanoparticles-lecithin modified montmorillonite into PDMS nanocomposites for antibacterial applications.